Aggregation-induced emission: Materials and biomedical applications

被引:5
作者
Liu, Bin [1 ]
机构
[1] Natl Univ Singapore, Chem & Biomol Engn Dept, Singapore, Singapore
关键词
LIGHT-UP BIOPROBE; AIE; PROBE; APOPTOSIS; ABLATION;
D O I
10.1557/mrs.2017.93
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
It is common knowledge that chromophore aggregation usually quenches light emission. The concept of aggregation-induced emission (AIE) changes this general belief and provides a new stage for the exploration of practical luminescent materials. The weak emission of AIE fluorogens (AIEgens) as molecular species and their bright fluorescence as nanoscopic aggregates distinguishes them from conventional organic luminophores and inorganic nanoparticles, making them ideal candidates for high-tech applications. This article summarizes the impact of AIEgens in biomedical applications.
引用
收藏
页码:458 / 462
页数:5
相关论文
共 22 条
[1]   Precise and Long-Term Tracking of Adipose-Derived Stem Cells and Their Regenerative Capacity via Superb Bright and Stable Organic Nanodots [J].
Ding, Dan ;
Mao, Duo ;
Li, Kai ;
Wang, Xiaomin ;
Qin, Wei ;
Liu, Rongrong ;
Chiam, David Shunzhong ;
Tomczak, Nikodem ;
Yang, Zhimou ;
Tang, Ben Zhong ;
Kong, Deling ;
Liu, Bin .
ACS NANO, 2014, 8 (12) :12620-12631
[2]   Bioprobes Based on AIE Fluorogens [J].
Ding, Dan ;
Li, Kai ;
Liu, Bin ;
Tang, Ben Zhong .
ACCOUNTS OF CHEMICAL RESEARCH, 2013, 46 (11) :2441-2453
[3]   Multifunctional AIEgens for Future Theranostics [J].
Feng, Guangxue ;
Liu, Bin .
SMALL, 2016, 12 (47) :6528-6535
[4]   A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria [J].
Feng, Guangxue ;
Yuan, Youyong ;
Fang, Hu ;
Zhang, Ruoyu ;
Xing, Bengang ;
Zhang, Guanxin ;
Zhang, Deqing ;
Liu, Bin .
CHEMICAL COMMUNICATIONS, 2015, 51 (62) :12490-12493
[5]   Aggregation-induced emission [J].
Hong, Yuning ;
Lam, Jacky W. Y. ;
Tang, Ben Zhong .
CHEMICAL SOCIETY REVIEWS, 2011, 40 (11) :5361-5388
[6]   Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing [J].
Li, Kai ;
Qin, Wei ;
Ding, Dan ;
Tomczak, Nikodem ;
Geng, Junlong ;
Liu, Rongrong ;
Liu, Jianzhao ;
Zhang, Xinhai ;
Liu, Hongwei ;
Liu, Bin ;
Tang, Ben Zhong .
SCIENTIFIC REPORTS, 2013, 3
[7]   Specific light-up bioprobes based on AIEgen conjugates [J].
Liang, Jing ;
Tang, Ben Zhong ;
Liu, Bin .
CHEMICAL SOCIETY REVIEWS, 2015, 44 (10) :2798-2811
[8]   Long wavelength excitable near-infrared fluorescent nanoparticles with aggregation-induced emission characteristics for image-guided tumor resection [J].
Liu, Jie ;
Chen, Chao ;
Ji, Shenglu ;
Liu, Qian ;
Ding, Dan ;
Zhao, Dan ;
Liu, Bin .
CHEMICAL SCIENCE, 2017, 8 (04) :2782-2789
[9]   Organic Dots Based on AIEgens for Two-Photon Fluorescence Bioimaging [J].
Lou, Xiaoding ;
Zhao, Zujin ;
Tang, Ben Zhong .
SMALL, 2016, 12 (47) :6430-6450
[10]   Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole [J].
Luo, JD ;
Xie, ZL ;
Lam, JWY ;
Cheng, L ;
Chen, HY ;
Qiu, CF ;
Kwok, HS ;
Zhan, XW ;
Liu, YQ ;
Zhu, DB ;
Tang, BZ .
CHEMICAL COMMUNICATIONS, 2001, (18) :1740-1741