Helicobacter pylori Infection

被引：558

作者：

McColl, Kenneth E. L. ^{[1
]}

机构：

[1] Univ Glasgow, Div Cardiovasc & Med Sci, Gardiner Inst, Glasgow G11 6NT, Lanark, Scotland

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2010年 / 362卷 / 17期

关键词：

PROTON-PUMP INHIBITOR; GASTRIC-CANCER; ANTIBIOTIC-RESISTANCE; RANDOMIZED-TRIAL; TRIPLE THERAPY; ERADICATION; METAANALYSIS; DYSPEPSIA; MANAGEMENT; 1ST-LINE;

D O I：

10.1056/NEJMcp1001110

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 29-year-old man presents with intermittent epigastric discomfort, without weight loss or evidence of gastrointestinal bleeding. He reports no use of aspirin or nonsteroidal antiinflammatory drugs (NSAIDs). Abdominal examination reveals epigastric tenderness. A serologic test for Helicobacter pylori is positive, and he receives a 10-day course of triple therapy (omeprazole, amoxicillin, and clarithromycin). Six weeks later, he returns with the same symptoms. How should his case be further evaluated and managed?

引用

页码：1597 / 1604

页数：8

共 50 条

[1]

[Anonymous], 1994, INFECT HELICOBACTER, V61, P177

[2] Randomised double blind controlled study of recurrence of gastric ulcer after treatment for eradication of Helicobacter pylori infection [J].

Axon, ATR ;

OMorain, CA ;

Bardhan, KD ;

Crowe, JP ;

Beattie, AD ;

Thompson, RPH ;

Smith, PM ;

Hollanders, FD ;

Baron, JH ;

Lynch, DAF ;

Dixon, MF ;

Tompkins, DS ;

Birrell, H ;

Gillon, KRW .

BRITISH MEDICAL JOURNAL, 1997, 314 (7080) :565-568

[3] American college of gastroenterology guideline on the management of Helicobacter pylori infection [J].

Chey, William D. ;

Wong, Benjamin C. Y. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 (08) :1808-1825

[4] Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia:: the Canadian adult dyspepsia empiric treatment -: Helicobacter pylori positive (CADET-Hp) randomised controlled trial [J].

Chiba, N ;

van Zanten, SJOV ;

Sinclair, P ;

Ferguson, RA ;

Escobedo, S ;

Grace, E .

BRITISH MEDICAL JOURNAL, 2002, 324 (7344) :1012-+

[5] Helicobacter pylori infection and the risk of development of esophageal adenocarcinoma [J].

de Martel, C ;

Llosa, AE ;

Farr, SM ;

Friedman, GD ;

Vogelman, JH ;

Orentreich, N ;

Corley, DA ;

Parsonnet, J .

JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (05) :761-767

[6]

Delaney B. C., 2003, COCHRANE DB SYST REV, V2

[7]

DELANEY BC, 2001, COCHRANE DB SYST REV, V3

[8] HELICOBACTER-PYLORI INFECTION AND ABNORMALITIES OF ACID-SECRETION IN PATIENTS WITH DUODENAL-ULCER DISEASE [J].

ELOMAR, EM ;

PENMAN, ID ;

ARDILL, JES ;

CHITTAJALLU, RS ;

HOWIE, C ;

MCCOLL, KEL .

GASTROENTEROLOGY, 1995, 109 (03) :681-691

[9] Recent developments in the epidemiology of Helicobacter pylori [J].

Everhart, JE .

GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2000, 29 (03) :559-+

[10] Meta-analysis:: the effect of antibiotic resistance status on the efficacy of triple and quadruple first-line therapies for Helicobacter pylori [J].

Fischbach, L. ;

Evans, E. L. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 26 (03) :343-357

← 1 2 3 4 5 →