SERINC Inhibits HIV-1 Env Induced Membrane Fusion and Slows Fusion Pore Enlargement

被引:0
|
作者
Markosyan, Ruben M. [1 ]
Liu, Shan-Lu [2 ]
Cohen, Fred S. [1 ]
机构
[1] Rush Univ, Med Ctr, Chicago, IL 60612 USA
[2] Univ Missouri, Sch Med, Dept Mol Microbiol & Immunol, Columbia, MO 65212 USA
关键词
D O I
10.1016/j.bpj.2016.11.472
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
406-Pos
引用
收藏
页码:79A / 79A
页数:1
相关论文
共 50 条
  • [21] Susceptibility to inhibitors of CD4-env binding correlates with membrane fusion: implications for HIV-1 entry
    Toma, J
    Wrin, T
    Chappey, C
    Fransen, S
    Lam, E
    Whitecomb, J
    Petropoulos, CJ
    Huang, W
    ANTIVIRAL THERAPY, 2005, 10 (04) : S160 - S160
  • [22] Six-helix bundle formation by HIV-1 gp41 is critical for fusion pore enlargement.
    Markosyan, RM
    Cohen, FS
    Melikian, GB
    BIOPHYSICAL JOURNAL, 2001, 80 (01) : 419A - 419A
  • [23] cGAS-mediated innate immunity spreads through HIV-1 env-induced membrane fusion sites from infected to uninfected primary HIV-1 target cells
    Ducroux, Aurelie
    Xu, Shuting
    Ponnurangam, Aparna
    Franz, Sergej
    Malassa, Angelina
    Ewald, Ellen
    Goffinet, Christine
    RETROVIROLOGY, 2016, 13
  • [24] Probing Structural Variation and Dynamics in the HIV-1 Env Fusion Gly- coprotein
    Munro, James B.
    Lee, Kelly K.
    CURRENT HIV RESEARCH, 2018, 16 (01) : 5 - 12
  • [25] FLUORESCENCE IMAGE CYTOMETRY OF HIV-1 ENV-CD4-MEDIATED FUSION
    PINE, PS
    WEAVER, JL
    ASZALOS, A
    MOLECULAR BIOLOGY OF THE CELL, 1995, 6 : 1049 - 1049
  • [26] HIV-1 Env Adopts an Open Trimer Conformation in Response to Fusion Inhibitor Resistance
    Keller, Paul
    Vessel, Russell
    Defeo, Chris
    Weiss, Carol
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2017, 74 : 85 - 85
  • [27] Enhancing the Immunogenicity of HIV-1 Env Trimers by Fusion to CD40 Ligand
    Melchers, M.
    De Vries, R.
    Berkhout, B.
    Sanders, R. W.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 23 - 23
  • [28] HIV-1 fusion core
    不详
    NATURE STRUCTURAL BIOLOGY, 1997, 4 (06): : 442 - 442
  • [30] The Energetics of Membrane Fusion from Binding, through Hemifusion, Pore Formation, and Pore Enlargement
    F.S. Cohen
    G.B. Melikyan
    The Journal of Membrane Biology, 2004, 199 : 1 - 14