Diterpenoid Alkaloids from Aconitum leucostomum and Their Antifeedant Activity

被引：9

作者：

Chen, Lin ^{[1
,2
,3
]}

Wang, Qian ^{[1
]}

Huang, Shuai ^{[1
]}

Shan, Lianhai ^{[1
]}

Gao, Feng ^{[1
]}

Zhou, Xianli ^{[1
,2
]}

机构：

[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Sichuan, Peoples R China

[2] Southwest Jiaotong Univ, Sch Mat Sci & Engn, Chengdu 610031, Sichuan, Peoples R China

[3] China West Normal Univ, Sch Chem & Chem Engn, Nanchong 637002, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 37卷 / 07期

基金：

中国国家自然科学基金;

关键词：

aconitum; Aconitum leucostomum; diterpenoid alkaloid; leucostonine; antifeedant activity;

D O I：

10.6023/cjoc201702021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new C-18 diterpenoid alkaloid, leucostonine (1), was isolated from the whole plant of Aconitum leucostomum Vorosch., together with twelve known diterpenoid alkaloids. Their structures were elucidated on the basis of extensive spectroscopic analysis, including HR-ESI-MS, 1D NMR and 2D NMR spectra. 12 compounds were tested for their antifeedant activity against larvae of Spodoptera exigua Hiibner. Anthranoyllycoctonine and avadharidine showed considerable potent antifeedant activity (EC50<1 mg/cm(2)), followed by N-acetylsepaconitine, finaconitine and N-deacetylappaconitine (EC50<2 mg/cm(2)).

引用

页码：1839 / 1843

页数：5

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