Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high-quality OCT/OCTA images, particularly with the handheld system, since both the operator hand tremor and subject motion can cause significant motion artifacts. In addition, having a large field of view and the ability of real-time data visualization are critical elements in rapid disease screening, reducing imaging time, and detecting peripheral retinal pathologies. The arrangement of optical components is less flexible in the handheld system due to the limitation of size and weight. In this paper, we introduce a 400-kHz, 55-degree field of view handheld OCT/OCTA system that has overcome many technical challenges as a portable OCT system as well as a high-speed OCTA system. We demonstrate imaging premature infants with retinopathy of prematurity (ROP) in the NICU, a patient with incontinentia pigmenti (IP), and a patient with X-linked retinoschisis (XLRS) in the OR using our handheld OCT system. Our design may have the potential for improving the diagnosis of retinal diseases and help provide a practical guideline for designing a flexible and portable OCT system.
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Ophthalmol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Avery, Robert A.
Hwang, Eugene I.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Hwang, Eugene I.
Ishikawa, Hiroshi
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Sch Med, Dept Ophthalmol, Eye Ctr,Eye & Ear Inst,Med Ctr,Ophthalmol & Visua, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Swanson Sch Engn, Dept Bioengn, Pittsburgh, PA USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Ishikawa, Hiroshi
Acosta, Maria T.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Acosta, Maria T.
Hutcheson, Kelly A.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Ophthalmol, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Hutcheson, Kelly A.
Santos, Domiciano
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Anesthesiol, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Santos, Domiciano
Zand, Dina J.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Genet, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Zand, Dina J.
Kilburn, Lindsay B.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Kilburn, Lindsay B.
Rosenbaum, Kenneth N.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Genet, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Rosenbaum, Kenneth N.
Rood, Brian R.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Rood, Brian R.
Schuman, Joel S.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Sch Med, Dept Ophthalmol, Eye Ctr,Eye & Ear Inst,Med Ctr,Ophthalmol & Visua, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Swanson Sch Engn, Dept Bioengn, Pittsburgh, PA USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Schuman, Joel S.
Packer, Roger J.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Choi, WooJhon
Moult, Eric M.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USA
Harvard Massachusetts Inst Technol, Div Hlth Sci & Technol, Cambridge, MA USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Moult, Eric M.
Waheed, Nadia K.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Waheed, Nadia K.
Adhi, Mehreen
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Adhi, Mehreen
Lee, ByungKun
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Lee, ByungKun
Lu, Chen D.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Lu, Chen D.
de Carlo, Talisa E.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
de Carlo, Talisa E.
Jayaraman, Vijaysekhar
论文数: 0引用数: 0
h-index: 0
机构:
Praevium Res Inc, Santa Barbara, CA USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Jayaraman, Vijaysekhar
Rosenfeld, Philip J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Rosenfeld, Philip J.
Duker, Jay S.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Duker, Jay S.
Fujimoto, James G.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Crane, Nicole J.
Huffman, Scott W.
论文数: 0引用数: 0
h-index: 0
机构:
Western Carolina Univ, Dept Chem & Phys, Cullowhee, NC 28723 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Huffman, Scott W.
Alemozaffar, Mehrdad
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Inst Urol, Norris Canc Ctr, Los Angeles, CA 90089 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Alemozaffar, Mehrdad
Gage, Frederick A.
论文数: 0引用数: 0
h-index: 0
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Gage, Frederick A.
Levin, Ira W.
论文数: 0引用数: 0
h-index: 0
机构:
NIDDK, Chem Phys Lab, Natl Inst Hlth, Bethesda, MD USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Levin, Ira W.
Elster, Eric A.
论文数: 0引用数: 0
h-index: 0
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD 20814 USA
Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Ophthalmol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Avery, Robert A.
Hwang, Eugene I.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Hwang, Eugene I.
Ishikawa, Hiroshi
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Sch Med, Dept Ophthalmol, Eye Ctr,Eye & Ear Inst,Med Ctr,Ophthalmol & Visua, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Swanson Sch Engn, Dept Bioengn, Pittsburgh, PA USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Ishikawa, Hiroshi
Acosta, Maria T.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Acosta, Maria T.
Hutcheson, Kelly A.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Ophthalmol, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Hutcheson, Kelly A.
Santos, Domiciano
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Anesthesiol, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Santos, Domiciano
Zand, Dina J.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Genet, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Zand, Dina J.
Kilburn, Lindsay B.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Kilburn, Lindsay B.
Rosenbaum, Kenneth N.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Genet, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Rosenbaum, Kenneth N.
Rood, Brian R.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Rood, Brian R.
Schuman, Joel S.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Sch Med, Dept Ophthalmol, Eye Ctr,Eye & Ear Inst,Med Ctr,Ophthalmol & Visua, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Swanson Sch Engn, Dept Bioengn, Pittsburgh, PA USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Schuman, Joel S.
Packer, Roger J.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Dept Oncol, Washington, DC 20010 USA
Childrens Natl Med Ctr, Brain Tumor Inst, Washington, DC 20010 USA
Childrens Natl Med Ctr, Ctr Neurosci & Behav, Washington, DC 20010 USAChildrens Natl Med Ctr, Gilbert Family Neurofibromatosis Inst, Washington, DC 20010 USA
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Choi, WooJhon
Moult, Eric M.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USA
Harvard Massachusetts Inst Technol, Div Hlth Sci & Technol, Cambridge, MA USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Moult, Eric M.
Waheed, Nadia K.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Waheed, Nadia K.
Adhi, Mehreen
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Adhi, Mehreen
Lee, ByungKun
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Lee, ByungKun
Lu, Chen D.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Lu, Chen D.
de Carlo, Talisa E.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
de Carlo, Talisa E.
Jayaraman, Vijaysekhar
论文数: 0引用数: 0
h-index: 0
机构:
Praevium Res Inc, Santa Barbara, CA USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Jayaraman, Vijaysekhar
Rosenfeld, Philip J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Rosenfeld, Philip J.
Duker, Jay S.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Univ, Med Ctr, New England Eye Ctr, Boston, MA 02111 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
Duker, Jay S.
Fujimoto, James G.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
MIT, Elect Res Lab, Cambridge, MA 02139 USAMIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Crane, Nicole J.
Huffman, Scott W.
论文数: 0引用数: 0
h-index: 0
机构:
Western Carolina Univ, Dept Chem & Phys, Cullowhee, NC 28723 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Huffman, Scott W.
Alemozaffar, Mehrdad
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Inst Urol, Norris Canc Ctr, Los Angeles, CA 90089 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Alemozaffar, Mehrdad
Gage, Frederick A.
论文数: 0引用数: 0
h-index: 0
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Gage, Frederick A.
Levin, Ira W.
论文数: 0引用数: 0
h-index: 0
机构:
NIDDK, Chem Phys Lab, Natl Inst Hlth, Bethesda, MD USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Levin, Ira W.
Elster, Eric A.
论文数: 0引用数: 0
h-index: 0
机构:
Naval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA
Walter Reed Natl Mil Med Ctr, Dept Surg, Bethesda, MD 20814 USA
Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USANaval Med Res Ctr, Dept Regenerat Med, Silver Spring, MD 20910 USA