PREPARATION AND PROPERTIES OF NOVEL BIOCOMPATIBLE PECTIN/SILICA CALCIUM PHOSPHATE HYBRIDS

被引：8

作者：

Abouzeid, Ragab E. ^{[1
]}

Abd El-Kader, Amal H. ^{[1
]}

Salama, Ahmed ^{[1
]}

Fahmy, Tamer Y. A. ^{[1
]}

El-Sakhawy, Mohamed ^{[1
]}

机构：

[1] Natl Res Ctr, Cellulose & Paper Dept, 33 El Bohouth Str,PO 12622, Giza, Egypt

来源：

CELLULOSE CHEMISTRY AND TECHNOLOGY | 2022年 / 56卷 / 3-4期

关键词：

pectin; silica; calcium phosphate; composite; COLORIMETRIC ASSAY; BONE; PECTIN; HYDROGELS;

D O I：

10.35812/CelluloseChemTechnol.2022.56.33

中图分类号：

TB3 [工程材料学]; TS [轻工业、手工业、生活服务业];

学科分类号：

0805 ; 080502 ; 0822 ;

摘要：

The development of bioactive polysaccharide-based hybrid materials is necessary for finding new alternatives in the field of biomaterials. As a bioactive water-soluble polysaccharide, pectin was used in this study to prepare reinforced silica gel monoliths through the sol-gel method. In-situ mineralization of calcium phosphate was achieved using calcium chloride and phosphate precursors. The properties of the pectin/silica/calcium phosphate hybrid were examined using FTIR, XRD and SEM/EDX techniques. Based on the results of the tests on kidney (Vero) cell lines, the pectin/silica/calcium phosphate hybrid demonstrated very mild cytotoxicity. In addition, the cytotoxicity of different hybrid concentrations was assessed with an MTT test, and the results demonstrated that their non-cytotoxicity for the concentrations investigated.

引用

页码：371 / 378

页数：8

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