Proliferative verrucous leukoplakia and its progression to oral carcinoma: report of three cases

被引:36
作者
Morton, Thomas H.
Cabay, Robert J.
Epstein, Joel B.
机构
[1] Univ Illinois, Coll Dent, Dept Oral Med & Diagnost Sci, Chicago, IL 60612 USA
[2] Univ Washington, Sch Dent, Dept Oral Biol, Seattle, WA 98195 USA
[3] Univ Washington, Sch Dent, Dept Oral Med, Seattle, WA 98195 USA
[4] Univ Illinois, Coll Med, Dept Pathol, Chicago, IL USA
[5] Univ Illinois, Coll Med, Dept Oral Med & Diagnost Sci, Chicago, IL USA
关键词
proliferative verrucous leukoplakia; oral cancer; squamous cell carcinoma; verrucous carcinoma;
D O I
10.1111/j.1600-0714.2007.00499.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Proliferative verrucous leukoplakia (PVL) is a distinct clinical form of oral leukoplakia defined by its progressive clinical course, changing clinical and histopathologic features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. We present three cases of PVL that progressed to carcinoma and discuss the histopathologic findings that may either hinder or assist in the diagnosis.
引用
收藏
页码:315 / 318
页数:4
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