Genetic and physical delineation of the region of the mouse deafness mutation shaker-2

被引：7
|
作者：
Wakabayashi, Y
Kikkawa, Y
Matsumoto, Y
Shinbo, T
Kosugi, S
Chou, D
Furuya, M
Jishage, K
Noda, T
Yonekawa, H
Kominami, R
机构：
[1] NIIGATA UNIV, SCH MED, DEPT BIOCHEM 1, NIIGATA 951, JAPAN
[2] TOKYO METROPOLITAN INST MED SCI, DEPT LAB ANIM SCI, BUNKYO KU, TOKYO 113, JAPAN
[3] JAPANESE FDN CANC RES, INST CANC, DEPT CELL BIOL, TOSHIMA KU, TOKYO 170, JAPAN
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 234卷 / 01期
关键词：
D O I：
10.1006/bbrc.1997.6595
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the entire nonrecombinant region of sh-2 and is therefore useful to facilitate the identification of genes in the sh-2 region. (C) 1997 Academic Press.
引用
收藏
页码：107 / 110
页数：4
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