Characteristics of chronic MS lesions in the cerebrum, brainstem, spinal cord, and optic nerve on T1-weighted MRI

被引：53

作者：

Gass, A

Filippi, M

Rodegher, ME

Schwartz, A

Comi, G

Hennerici, MG

机构：

[1] Univ Heidelberg, Klinikum Mannheim, Neurol Klin, D-68137 Mannheim, Germany

[2] Univ Heidelberg, Dept Neurol, D-68137 Mannheim, Germany

[3] Univ Milan, Osped San Raffaele, Dept Neurol, Sci Inst,MS Biosignal Anal Ctr, I-20122 Milan, Italy

来源：

NEUROLOGY | 1998年 / 50卷 / 02期

关键词：

D O I：

10.1212/WNL.50.2.548

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We analyzed the prevalence of severely hypointense lesions on T1-weighted MRI in the brainstem, spinal cord, and optic nerve from 65 patients with MS. About half of 1,274 supratentorial lesions were classified as severely hypointense. Severe hypointensity was not seen in the optic nerve and spinal cord, and in only one of 168 chronic brainstem lesions. Tissue destruction in the brainstem, spinal cord, and optic nerve of MS patients does not usually result in severely hypointense lesions.

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页码：548 / 550

页数：3

相关论文

共 10 条

[1] CORRELATIONS BETWEEN CHANGES IN DISABILITY AND T-2-WEIGHTED BRAIN MRI ACTIVITY IN MULTIPLE-SCLEROSIS - A FOLLOW-UP-STUDY [J].

FILIPPI, M ;

PATY, DW ;

KAPPOS, L ;

BARKHOF, F ;

COMPSTON, DAS ;

THOMPSON, AJ ;

ZHAO, GJ ;

WILES, CM ;

MCDONALD, WI ;

MILLER, DH .

NEUROLOGY, 1995, 45 (02) :255-260

[2] Quantitative assessment of MRI lesion load in multiple sclerosis - A comparison of conventional spin-echo with fast fluid-attenuated inversion recovery [J].

Filippi, M ;

Yousry, T ;

Baratti, C ;

Horsfield, MA ;

Mammi, S ;

Becker, C ;

Voltz, R ;

Spuler, S ;

Campi, A ;

Reiser, MF ;

Comi, G .

BRAIN, 1996, 119 :1349-1355

[3]

FILIPPI M, 1988, IN PRESS AJNR AM J N

[4] HIGH-RESOLUTION MAGNETIC-RESONANCE-IMAGING OF THE ANTERIOR VISUAL PATHWAY IN PATIENTS WITH OPTIC NEUROPATHIES USING FAST SPIN-ECHO AND PHASED-ARRAY LOCAL COILS [J].

GASS, A ;

BARKER, GJ ;

MACMANUS, D ;

SANDERS, M ;

RIORDANEVA, P ;

TOFTS, PS ;

THORPE, J ;

MCDONALD, WI ;

MOSELEY, IF ;

MILLER, DH .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1995, 58 (05) :562-569

[5] SPINAL-CORD MRI USING MULTIARRAY COILS AND FAST SPIN-ECHO .2. FINDINGS IN MULTIPLE-SCLEROSIS [J].

KIDD, D ;

THORPE, JW ;

THOMPSON, AJ ;

KENDALL, BE ;

MOSELEY, IF ;

MACMANUS, DG ;

MCDONALD, WI ;

MILLER, DH .

NEUROLOGY, 1993, 43 (12) :2632-2637

[6]

LOSSEFF NA, 1996, BRAIN, V119, P101

[7]

MILLER DH, 1994, ANN NEUROL, V36, P591

[8] CORRELATION OF MAGNETIC-RESONANCE IMAGING WITH NEUROPSYCHOLOGICAL TESTING IN MULTIPLE-SCLEROSIS [J].

RAO, SM ;

LEO, GJ ;

HAUGHTON, VM ;

AUBINFAUBERT, PS ;

BERNARDIN, L .

NEUROLOGY, 1989, 39 (02) :161-166

[9]

VANWALDERVEEN MAA, 1996, J NEUROL S2, V243, pS18

[10] THE PATHOPHYSIOLOGY OF ACUTE OPTIC NEURITIS - AN ASSOCIATION OF GADOLINIUM LEAKAGE WITH CLINICAL AND ELECTROPHYSIOLOGICAL DEFICITS [J].

YOUL, BD ;

TURANO, G ;

MILLER, DH ;

TOWELL, AD ;

MACMANUS, DG ;

MOORE, SG ;

JONES, SJ ;

BARRETT, G ;

KENDALL, BE ;

MOSELEY, IF ;

TOFTS, PS ;

HALLIDAY, AM ;

MCDONALD, WI .

BRAIN, 1991, 114 :2437-2450