Gene expression in brain: A window on ethanol dependence, neuroadaptation, and preference

被引：32
作者：
Hoffman, PL
Miles, M
Edenberg, HJ
Sommer, W
Tabakoff, B
Wehner, JM
Lewohl, J
机构：
[1] Univ Colorado, Dept Pharmacol, Denver, CO 80202 USA
[2] Univ Colorado, Inst Behav Genet, Boulder, CO USA
[3] Virginia Commonwealth Univ, Dept Pharmacol & Toxicol, Richmond, VA USA
[4] Indiana Univ, Sch Med, Dept Biochem & Mol Biol, Indianapolis, IN 46204 USA
[5] Huddinge Univ Hosp, Karolinska Inst, Addict Ctr S, Dept NEUROTEC, Stockholm, Sweden
[6] Univ Queensland, Dept Biochem, St Lucia, Qld, Australia
来源：
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH | 2003年 / 27卷 / 02期
关键词：
DNA microarrays; gene expression; selected lines; transgenics; null mutants; alcohol preference; alcohol tolerance; alcoholism;
D O I：
10.1097/01.ALC.0000060101.89334.11
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.
引用
收藏
页码：155 / 168
页数：14
相关论文
共 72 条
[61]   Differential expression of diacylglycerol kinase iota and L18A mRNAs in the brains of alcohol-preferring AA and alcohol-avoiding ANA rats [J].
Sommer, W ;
Arlinde, C ;
Caberlotto, L ;
Thorsell, A ;
Hyytia, P ;
Heilig, M .
MOLECULAR PSYCHIATRY, 2001, 6 (01) :103-108
[62]   EVIDENCE FOR GENETIC CORRELATION OF HYPNOTIC EFFECTS AND CEREBELLAR PURKINJE NEURON DEPRESSION IN RESPONSE TO ETHANOL IN MICE [J].
SPUHLER, K ;
HOFFER, B ;
WEINER, N ;
PALMER, M .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1982, 17 (03) :569-578
[63]   Regional central nervous system densities of delta-opioid receptors in alcohol-preferring P, alcohol-nonpreferring NP, and unselected Wistar rats [J].
Strother, WN ;
Chernet, EJ ;
Lumeng, L ;
Li, TK ;
McBride, WJ .
ALCOHOL, 2001, 25 (01) :31-38
[64]   Structure of RGS4 bound to AlF4--activated G(i alpha 1): Stabilization of the transition state for GTP hydrolysis [J].
Tesmer, JJG ;
Berman, DM ;
Gilman, AG ;
Sprang, SR .
CELL, 1997, 89 (02) :251-261
[65]   Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression [J].
Thibault, C ;
Lai, CQ ;
Wilke, N ;
Duong, B ;
Olive, MF ;
Rahman, S ;
Dong, HL ;
Hodge, CW ;
Lockhart, DJ ;
Miles, MF .
MOLECULAR PHARMACOLOGY, 2000, 58 (06) :1593-1600
[66]   SIGNIFICANT REVERSIBILITY OF ALCOHOLIC BRAIN SHRINKAGE WITHIN 3 WEEKS OF ABSTINENCE [J].
TRABERT, W ;
BETZ, T ;
NIEWALD, M ;
HUBER, G .
ACTA PSYCHIATRICA SCANDINAVICA, 1995, 92 (02) :87-90
[67]   INTRAGASTRIC SELF-INFUSION OF ETHANOL BY ETHANOL-PREFERRING AND ETHANOL-NONPREFERRING LINES OF RATS [J].
WALLER, MB ;
MCBRIDE, WJ ;
GATTO, GJ ;
LUMENG, L ;
LI, TK .
SCIENCE, 1984, 225 (4657) :78-80
[68]   TOPOLOGY OF CNS MYELIN PROTEOLIPID PROTEIN - EVIDENCE FOR THE NONENZYMATIC GLYCOSYLATION OF EXTRACYTOPLASMIC DOMAINS IN NORMAL AND DIABETIC ANIMALS [J].
WEIMBS, T ;
STOFFEL, W .
BIOCHEMISTRY, 1994, 33 (34) :10408-10415
[69]   GREATER ABUNDANCE OF SEROTONIN(1A) RECEPTOR IN SOME BRAIN-AREAS OF ALCOHOL-PREFERRING (P) RATS COMPARED TO NONPREFERRING (NP) RATS [J].
WONG, DT ;
REID, LR ;
LI, TK ;
LUMENG, L .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1993, 46 (01) :173-177
[70]   How do 14-3-3 proteins work? - Gatekeeper phosphorylation and the molecular anvil hypothesis [J].
Yaffe, MB .
FEBS LETTERS, 2002, 513 (01) :53-57
12345678