Gene expression in brain: A window on ethanol dependence, neuroadaptation, and preference

被引:32
作者
Hoffman, PL
Miles, M
Edenberg, HJ
Sommer, W
Tabakoff, B
Wehner, JM
Lewohl, J
机构
[1] Univ Colorado, Dept Pharmacol, Denver, CO 80202 USA
[2] Univ Colorado, Inst Behav Genet, Boulder, CO USA
[3] Virginia Commonwealth Univ, Dept Pharmacol & Toxicol, Richmond, VA USA
[4] Indiana Univ, Sch Med, Dept Biochem & Mol Biol, Indianapolis, IN 46204 USA
[5] Huddinge Univ Hosp, Karolinska Inst, Addict Ctr S, Dept NEUROTEC, Stockholm, Sweden
[6] Univ Queensland, Dept Biochem, St Lucia, Qld, Australia
关键词
DNA microarrays; gene expression; selected lines; transgenics; null mutants; alcohol preference; alcohol tolerance; alcoholism;
D O I
10.1097/01.ALC.0000060101.89334.11
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.
引用
收藏
页码:155 / 168
页数:14
相关论文
共 72 条
[51]   Thinning of the corpus callosum in older alcoholic men: A magnetic resonance imaging study [J].
Pfefferbaum, A ;
Lim, KO ;
Desmond, JE ;
Sullivan, EV .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1996, 20 (04) :752-757
[52]   INCREASE IN BRAIN CEREBROSPINAL-FLUID VOLUME IS GREATER IN OLDER THAN IN YOUNGER ALCOHOLIC PATIENTS - A REPLICATION STUDY AND CT/MRI COMPARISON [J].
PFEFFERBAUM, A ;
SULLIVAN, EV ;
ROSENBLOOM, MJ ;
SHEAR, PK ;
MATHALON, DH ;
LIM, KO .
PSYCHIATRY RESEARCH-NEUROIMAGING, 1993, 50 (04) :257-274
[53]  
PROCTOR WR, 2000, SOC NEUR ABSTR
[54]   Computational analysis of microarray data [J].
Quackenbush, J .
NATURE REVIEWS GENETICS, 2001, 2 (06) :418-427
[55]   Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol [J].
Rimondini, R ;
Arlinde, C ;
Sommer, W ;
Heilig, M .
FASEB JOURNAL, 2002, 16 (01) :27-35
[56]   Excessive ethanol drinking following a history of dependence: Animal model of allostasis [J].
Roberts, AJ ;
Heyser, CJ ;
Cole, M ;
Griffin, P ;
Koob, GF .
NEUROPSYCHOPHARMACOLOGY, 2000, 22 (06) :581-594
[57]   LONG-TERM ETHANOL ADMINISTRATION METHODS FOR RATS - ADVANTAGES OF INHALATION OVER INTUBATION OR LIQUID DIETS [J].
ROGERS, J ;
WIENER, SG ;
BLOOM, FE .
BEHAVIORAL AND NEURAL BIOLOGY, 1979, 27 (04) :466-486
[58]   Regional and strain-specific gene expression mapping in the adult mouse brain [J].
Sandberg, R ;
Yasuda, R ;
Pankratz, DG ;
Carter, TA ;
Del Rio, JA ;
Wodicka, L ;
Mayford, M ;
Lockhart, DJ ;
Barlow, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) :11038-11043
[59]   Identification of neuroendocrine-specific protein as an ethanol-regulated gene with mRNA differential display [J].
Schafer, GL ;
Crabbe, JC ;
Wiren, KM .
MAMMALIAN GENOME, 1998, 9 (12) :979-982
[60]   VOLUMETRIC MAGNETIC-RESONANCE-IMAGING QUANTIFICATION OF LONGITUDINAL BRAIN CHANGES IN ABSTINENT ALCOHOLICS [J].
SHEAR, PK ;
JERNIGAN, TL ;
BUTTERS, N .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1994, 18 (01) :172-176