Gene expression in brain: A window on ethanol dependence, neuroadaptation, and preference

被引：32

作者：

Hoffman, PL

Miles, M

Edenberg, HJ

Sommer, W

Tabakoff, B

Wehner, JM

Lewohl, J

机构：

[1] Univ Colorado, Dept Pharmacol, Denver, CO 80202 USA

[2] Univ Colorado, Inst Behav Genet, Boulder, CO USA

[3] Virginia Commonwealth Univ, Dept Pharmacol & Toxicol, Richmond, VA USA

[4] Indiana Univ, Sch Med, Dept Biochem & Mol Biol, Indianapolis, IN 46204 USA

[5] Huddinge Univ Hosp, Karolinska Inst, Addict Ctr S, Dept NEUROTEC, Stockholm, Sweden

[6] Univ Queensland, Dept Biochem, St Lucia, Qld, Australia

来源：

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH | 2003年 / 27卷 / 02期

关键词：

DNA microarrays; gene expression; selected lines; transgenics; null mutants; alcohol preference; alcohol tolerance; alcoholism;

D O I：

10.1097/01.ALC.0000060101.89334.11

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.

引用

页码：155 / 168

页数：14

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