Simultaneous determination of adenosine and adenosine-5′-triphosphate at nanogold modified indium tin oxide electrode by osteryoung square-wave voltammetry

Simultaneous determination of adenosine and adenosine-5'-triphosphate has been described using nanogold modified indium tin oxide electrode. Gold nanoparticles catalyze adenosine oxidation which results in increasing separation of oxidation peaks of adenosine and ATP, making it possible to determine adenosine and adenosine-5'-triphosphate simultaneously. The detection limits for adenosine and ATP were found as 0.07 mu M and 0.10 mu M respectively with sensitivity 22.9 nA mu M-1 and 20.9 nA mu M-1. The proposed method was also used for sensing the compounds in biological samples. Influence of various square-wave parameters and different pH conditions on peak current has also been reported.