Mitochondrial Plasticity with Exercise Training and Extreme Environments

被引:27
作者
Boushel, Robert [1 ]
Lundby, Carsten [2 ]
Qvortrup, Klaus [3 ]
Sahlin, Kent [1 ]
机构
[1] Swedish Sch Sport & Hlth Sci, Astrand Lab, S-11486 Stockholm, Sweden
[2] Univ Zurich, Inst Physiol, Ctr Integrat Human Physiol, Zurich, Switzerland
[3] Univ Copenhagen, Fac Hlth & Med Sci, Dept Biomed Sci, Core Facil Integrated Microscopy, Copenhagen, Denmark
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2014年 / 42卷 / 04期
关键词
exercise training; mitochondria; OXPHOS; substrates; coupling; environment; HUMAN SKELETAL-MUSCLE; FAT OXIDATION RATES; ENDURANCE EXERCISE; PHYSICAL-ACTIVITY; FIBER TYPES; HUMANS; CAPACITY; ADAPTATIONS; EFFICIENCY; ALTITUDE;
D O I
10.1249/JES.0000000000000025
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.
引用
收藏
页码:169 / 174
页数:6
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