Age at first cannabis use moderates EEG markers of recovery from cannabis

被引：8

作者：

Allsop, David J. ^{[1
,2
]}

Copeland, Jan ^{[3
]}

机构：

[1] Univ Sydney, Fac Sci, Sch Psychol, Psychopharmacol Lab, Sydney, NSW 2006, Australia

[2] Univ Sydney, Fac Sci, Discipline Addict Med, Sydney, NSW 2006, Australia

[3] Univ New S Wales, Fac Med, NCPIC, Sydney, NSW, Australia

来源：

JOURNAL OF SUBSTANCE USE | 2016年 / 21卷 / 04期

关键词：

Cannabis; cannabis abstinence; EEG; recovery; CEREBRAL-BLOOD-FLOW; INFERIOR FRONTAL GYRUS; MARIJUANA USE; PERFUSION; ABSTINENCE; ABNORMALITIES; WITHDRAWAL; FREQUENCY; SEQUELAE; VOLUME;

D O I：

10.3109/14659891.2015.1040090

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Background and Aims: Cannabis-induced cerebral perfusion deficits cause reduced electroencephalogram spectral power. In previous work, spectral power did not recover with cannabis abstinence. This study uses EEG to explore moderators of recovery during cannabis abstinence. Methods: A within-subject prospective community-based cannabis abstinence study was conducted with 10 cannabis-dependent participants. Resting EEG was measured before and after 14 days of abstinence at frontal and occipital electrodes. Demographic, drug use and withdrawal data were explored as moderators of EEG recovery. Results: In adjusted models, age at first cannabis use predicted EEG power change in the beta/gamma frequency band at frontal electrodes, as did participant age. Conclusion: Age at first cannabis use may moderate increases in EEG beta/gamma band power with cannabis abstinence.

引用

页码：400 / 406

页数：7

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