Endurance exercise causes adverse changes in some hematological and physio-biochemical indices in ponies under high altitude stress condition

The ponies have immense relevance for logistic support for civil population and troops in hilly and high altitude areas. There is no infonnation on specific biomarkers of endurance performance under high altitude stress condition, which could be supportive in the identification of elite ponies for deployment at high altitude. Therefore, the present study was conducted to evaluate the physiological responses, hematological, biochemical, metabolic, and antioxidant biomarker during endurance exercise in ponies at high altitude. For this study, total 5 mares were put on endurance exercise at 4-6 m/sec speed for 30 min on 30 m track situated at 3,500 m altitude for 28 days period. The result showed a significant change in physiological responses, and some hematological, biochemical, metabolic and antioxidant parameters viz. glutathione peroxidase, creatinine kinase-MB, lactic acid, total protein, glucose, hexokinase, cortisol, and interleukin-6 level at different phase of endurance exercise. In conclusion, this study showed the alteration in physiological responses and some hematological and physio-biochemical metabolic parameters during the endurance exercise. Hence, these parameters could be considered as biomarkers for evaluation of endurance performance in ponies at high altitude before putting them under load carrying deployment.