Acceptance of Chemo-prophylaxis for Latent Tuberculosis Infection among High School/College Student Contacts of Tuberculosis Patients in Shanghai, China

被引：15

作者：

Li Yang ^{[1
,2
]}

Zheng Yi Hui ^{[3
]}

Lu Li Ping ^{[4
]}

Yang Mei Xia ^{[5
]}

Zhou Chang Ming ^{[1
,2
]}

Yuan Zheng An ^{[6
]}

Hu Yi ^{[1
,2
]}

Xu Biao ^{[1
,2
,7
]}

机构：

[1] Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai 200032, Peoples R China

[2] Fudan Univ, Sch Publ Hlth, Key Lab Publ Hlth Safety, Minist Educ, Shanghai 200032, Peoples R China

[3] Putuo Dist Ctr Dis Control & Prevent, Shanghai 200333, Peoples R China

[4] Songjiang Dist Ctr Dis Control & PreVent, Shanghai 201620, Peoples R China

[5] Xuhui Dist Ctr Dis Control & PreVent, Shanghai 200237, Peoples R China

[6] Shanghai Ctr Dis Control & PreVent, Shanghai 200336, Peoples R China

[7] Karolinska Inst, Dept Publ Hlth Sci, S-17177 Stockholm, Sweden

来源：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES | 2018年 / 31卷 / 04期

关键词：

D O I：

10.3967/bes2018.041

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Student contacts of tuberculosis (TB) cases are susceptible to latent tuberculosis infection (LTBI), and chemo-prophylaxis can reduce the risk of active TB among them. This study aimed to assess the acceptance of chemo-prophylaxis for LTBI among students, and their concerns regarding TB and its preventive treatment. A total of 560 students contacts were included in the investigation. The extent of contact was categorized from high to low (4 levels) with 12.9% of the students being close contacts. About 87.0% of the students were willing to receive chemo-prophylaxis if diagnosed with, LTBI, whereas 73 students declined. Students with a higher level of knowledge about TB (aOR = 1.11) or close contact with TB patients (aOR = 4.30) were more likely to accept treatment. To conclude, education regarding TB transmission is necessary. Moreover, LTBI detection should be integrated into the current school-based TB contact investigation.

引用

页码：317 / +

页数：6

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