Surface modification of poly-ε-caprolactone electrospun fibrous scaffolds using plasma discharge with sputter deposition of a titanium target

被引：23
|
作者：
Barbarash, L. S. [1 ]
Bolbasov, E. N. [2 ]
Antonova, L. V. [1 ]
Matveeva, V. G. [1 ]
Velikanova, E. A. [1 ]
Shesterikov, E. V. [2 ]
Anissimov, Y. G. [3 ]
Tverdokhlebov, S. I. [2 ]
机构：
[1] Res Inst Complex Issues Cardiovasc Dis, Fed State Budgetary Inst, 6 Sosnovy Blvd, Kemerovo 650002, Russia
[2] Tomsk Polytech Univ, 30 Lenin Ave, Tomsk 634050, Russia
[3] Griffith Univ, Sch Nat Sci, Engn Dr, Southport, Qld 4222, Australia
来源：
MATERIALS LETTERS | 2016年 / 171卷
基金：
俄罗斯科学基金会;
关键词：
Biomaterials; Poly-epsilon-caprolactone; Fibrous scaffold; Magnetron discharge; Plasma treatment; HYDROXYAPATITE TARGET; FILM;
D O I：
10.1016/j.matlet.2016.02.062
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Poly-epsilon-caprolactone (PCL) biodegradable fibrous scaffolds were modified by plasma of magnetron discharge with titanium target sputtering. The influence of the plasma treatment time on the structure and properties of the electrospun scaffolds was investigated. It was shown that increasing the plasma treatment time increases hydrophilicity of scaffolds by increasing the content of titanium and oxygen, as well as increasing the size and number of pores on the fibers surface without changing the mean diameter and volume fraction of the scaffolds. In vitro studies demonstrated that the plasma treatment within the chosen time intervals increases the adhesion of cells to the scaffolds, but at the same time it causes the decline in cell viability when increased to 9 min. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：87 / 90
页数：4
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