Effect of vitamin D deficiency on cardiovascular risk

被引：2

作者：

Cormier, C. ^{[1
]}

Courbebaisse, M. ^{[2
]}

Maury, E. ^{[1
]}

Thervet, E. ^{[3
]}

Souberbielle, J. -C. ^{[4
]}

机构：

[1] Univ Paris 05, Hop Cochin, AP HP, Serv Rhumatol, F-75014 Paris, France

[2] Univ Paris 05, Hop Tenon, AP HP, Serv Nephrol & Dialyses, F-75020 Paris, France

[3] Univ Paris 05, Hop Necker, AP HP, Serv Transplantat Renale, F-75015 Paris, France

[4] Univ Paris 05, Hop Necker Enfants Malad, Serv Explorat Fonct, F-75015 Paris, France

来源：

JOURNAL DES MALADIES VASCULAIRES | 2010年 / 35卷 / 04期

关键词：

Vitamin D; Cardiovascular risk; STAGE RENAL-DISEASE; D-RECEPTOR VDR; NF-KAPPA-B; PARATHYROID-HORMONE; BLOOD-PRESSURE; CALCIUM SUPPLEMENTATION; 25-HYDROXYVITAMIN D; INTRAVENOUS CALCITRIOL; HEMODIALYSIS-PATIENTS; IMPROVED SURVIVAL;

D O I：

10.1016/j.jmv.2010.05.001

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Vitamin D deficiency affects almost 50% of the population worldwide. Besides its classical effects on bone and calcium metabolism, vitamin D displays a wide spectrum of non classical effects. Among these effects, those targeting the cardiovascular system are mostly documented by observational, experimental and small intervention trials that most often evaluated intermediate parameters. The time has now come for large placebo-controlled trials targeting clinical endpoints such as the incidence of major cardiovascular events and mortality. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：235 / 241

页数：7

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