Spermidine alkaloid and glycosidic constituents of Vietnamese Homalium cochinchinensis

被引:3
作者
Addo, Ermias Mekuria [1 ]
Ren, Yulin [1 ]
Anaya-Eugenio, Gerardo D. [1 ]
Ninh Tran Ngoc [2 ]
Rakotondraibe, Harinantenaina L. [1 ]
de Blanco, Esperanza J. Carcache [1 ]
Soejarto, Djaja D. [3 ,4 ]
Kinghorn, A. Douglas [1 ]
机构
[1] Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA
[2] Vietnam Acad Sci & Technol, Hanoi, Vietnam
[3] Univ Illinois, Coll Pharm, Dept Pharmaceut Sci, Chicago, IL 60612 USA
[4] Field Museum Nat Hist, Sci & Educ, Chicago, IL 60605 USA
关键词
Homalium cochinchinensis; Spermidine alkaloids; Dovyalicins; Glycosides; Secondary metabolites; DERIVATIVES; GLUCOSIDES;
D O I
10.1016/j.phytol.2021.04.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Phytochemical investigation of the aerial parts of Homalium cochinchinensis led to the isolation of secondary metabolites belonging to the spermidine alkaloid, glycoside, depsidone and phenol classes. Of the eleven secondary metabolites isolated in this study, two spermidine alkaloids, dovyalicins H (1) and I (2), which belong to a rare group among this class, and six glycosides (3-8) are previously undescribed. The structures of all new isolates were determined by interpretation of spectroscopic and spectrometric data. In this report, the structural elucidation of these unprecedented secondary metabolites (1-8) is described.
引用
收藏
页码:154 / 162
页数:9
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