Opposing effects of IL-1α and IL-1β on malignancy patterns -: Tumor cell-associated IL-1α potentiates anti-tumor immune responses and tumor regression, whereas IL-1β potentiates invasiveness

被引：0
|
作者：
Apte, RN [1 ]
Dvorkin, T
Song, XP
Fima, E
Krelin, Y
Yulevitch, A
Gurfinkel, R
Werman, A
White, RM
Argov, S
Shendler, Y
Bjorkdahl, O
Dohlsten, M
Zoller, M
Segal, S
Voronov, E
机构：
[1] Ben Gurion Univ Negev, Fac Hlth Sci, Dept Microbiol & Immunol, IL-84105 Beer Sheva, Israel
[2] Ben Gurion Univ Negev, Canc Res Ctr, IL-84105 Beer Sheva, Israel
[3] Soroka Med Ctr, Dept Pathol, IL-84101 Beer Sheva, Israel
[4] Univ Lund, Lund, Sweden
[5] German Canc Res Ctr, D-6900 Heidelberg, Germany
来源：
BIOLOGY AND PATHOLOGY OF INNATE IMMUNITY MECHANISMS | 2000年 / 479卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：277 / 288
页数：12
相关论文
共 50 条
  • [1] Differential roles of IL-1α and IL-1β in tumor progression
    Tian, T.
    Jin, Q.
    Fuhlbrigge, R. C.
    Kupper, T. S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S127 - S127
  • [2] Differential effects of IL-1α and IL-1β on tumorigenicity patterns and invasiveness
    Song, XP
    Voronov, E
    Dvorkin, T
    Fima, E
    Cagnano, E
    Benharroch, D
    Shendler, Y
    Bjorkdahl, O
    Segal, S
    Dinarello, CA
    Apte, RN
    JOURNAL OF IMMUNOLOGY, 2003, 171 (12): : 6448 - 6456
  • [3] ANTI-TUMOR EFFICACY OF IL-1 AND IL-2
    BUBENIK, J
    INDROVA, M
    HOLAN, V
    FOLIA BIOLOGICA, 1988, 34 (01) : 42 - 47
  • [4] IL-1 is required for tumor invasiveness and angiogenesis
    Voronov, E
    Shouval, DS
    Krelin, Y
    Cagnano, E
    Benharroch, D
    Iwakura, Y
    Dinarello, CA
    Apte, RN
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (05) : 2645 - 2650
  • [5] Unique versus redundant functional of IL-1α and IL-1β in the tumor microenvironment
    Voronov, Elena
    Dotan, Shahar
    Krelin, Yakov
    Song, Xiaoping
    Elkabets, Moshe
    Carmi, Yaron
    Rider, Peleg
    Cohen, Idan
    Romzova, Marianna
    Kaplanov, Irena
    Apte, Ron N.
    FRONTIERS IN IMMUNOLOGY, 2013, 4
  • [6] Differential regulation of epidermal cell tumor-antigen presentation by IL-1α and IL-1β
    Beissert, S
    Hosoi, J
    Stratigos, A
    Brissette, J
    Grabbe, S
    Schwarz, T
    Granstein, RD
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 111 (04) : 609 - 615
  • [7] Opposing effects of fibrosarcoma cell-derived IL-1α and IL-1β on immune response induction
    Marhaba, Rachid
    Nazarenko, Irina
    Knoefler, Daniela
    Reich, Eli
    Voronov, Elena
    Vitacolonna, Mario
    Hildebrand, Dagmar
    Elter, Elena
    Apte, Ron N.
    Zoeller, Margot
    INTERNATIONAL JOURNAL OF CANCER, 2008, 123 (01) : 134 - 145
  • [8] IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice
    Terlizzi, Michela
    Colarusso, Chiara
    Popolo, Ada
    Pinto, Aldo
    Sorrentino, Rosalinda
    ONCOTARGET, 2016, 7 (36) : 58181 - 58192
  • [9] IL-1 Signaling in Tumor Microenvironment
    Zhang, Weizhou
    Borcherding, Nicholas
    Kolb, Ryan
    TUMOR MICROENVIRONMENT: THE ROLE OF INTERLEUKINS, PT A, 2020, 1240 : 1 - 23
  • [10] Differential anti-tumor effects of interleukin-1 (IL-1) alpha and IL-1 beta in cytokine gene-transfer approaches in tumor immunotherapy
    Apte, RN
    Dvorkin, T
    Fima, E
    Song, X
    White, RM
    Ofir, R
    Benharroch, D
    Argov, S
    Werman, A
    Bjorkdahl, O
    Wingren, AG
    Dohlsten, M
    Zoller, M
    Segal, S
    Voronov, E
    10TH INTERNATIONAL CONGRESS ON IMMUNOLOGY, VOLS 1 AND 2, 1998, : 1383 - 1389
12345