Biological activity of phenolic lipids

被引：183

作者：

Stasiuk, Maria ^{[1
]}

Kozubek, A. ^{[1
]}

机构：

[1] Univ Wroclaw, Fac Biotechnol, Dept Lipids & Liposomes, PL-51148 Wroclaw, Poland

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2010年 / 67卷 / 06期

关键词：

Amphiphiles; Anacardic acids; Cashew nut shell liquid (CNSL); Membrane-perturbing properties; Phenolic lipids; Resorcinolic lipids; CASHEW ANACARDIUM-OCCIDENTALE; NUT-SHELL LIQUID; RESISTANT STAPHYLOCOCCUS-AUREUS; GINKGO-BILOBA L; GLYCEROL-3-PHOSPHATE DEHYDROGENASE INHIBITORS; LONG-CHAIN; 5-NORMAL-ALKYLRESORCINOLS; POTENT INSECTICIDAL ACTIVITY; 6-NONADECYL SALICYLIC-ACID; GRAIN RESORCINOLIC LIPIDS; SMALL-MOLECULE MODULATORS;

D O I：

10.1007/s00018-009-0193-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phenolic lipids are a very diversified group of compounds derived from mono and dihydroxyphenols, i.e., phenol, catechol, resorcinol, and hydroquinone. Due to their strong amphiphilic character, these compounds can incorporate into erythrocytes and liposomal membranes. In this review, the antioxidant, antigenotoxic, and cytostatic activities of resorcinolic and other phenolic lipids are described. The ability of these compounds to inhibit bacterial, fungal, protozoan and parasite growth seems to depend on their interaction with proteins and/or on their membrane-disturbing properties.

引用

页码：841 / 860

页数：20

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