Technological innovation is the engine of economic growth and got high attention by many aspects. In order to increase the speed and performance of innovation, many developing Countries have tried a lot of innovation strategies, such as comparative strategy and following-up strategy and so on. If the developing Countries adopt following-Lip strategies and try to exploit innovation in the same field with developed countries, as the result of Stackelberg Model, the developed will always take the place of lead and the developing ones cannot catch LIP with it forever. However, the strategy of industrial clusters can provide opportunities and possibilities to increase innovation. The case in this paper is Chinese manufacturing industry, econometric model and game analysis model are used to find the mechanism between industrial cluster and technological innovation and political measurement to speed leapfrogging in technological innovation for developing countries. The empirical results show that there are apparent clusters in industry and innovation the numbers of new products have significant positive relations with scientists and R&D expenditure, and the number of inventive patents has significant positive relation with R&D expenditure and no significant relation with number of scientist.