Predictive value of diaphragmatic rapid shallow breathing index in mechanical ventilation weaning: a systematic review and meta-analysis

Background: Mechanical ventilation weaning is a multifactorial process. D-RSBI cannot only reflect the respiratory function but also the diaphragmatic function with the bedside ultrasound technique. Objective: This review aimed to assess the predictive value of diaphragmatic rapid shallow breathing index (D-RSBI) of weaning outcome. Method: Databases were systematically reviewed including PubMed, Cochrane Library, Embase, CNKI and WanFang Data. Sensitivity and specificity were pooled with random effects models. Results: Nine studies met the inclusion criteria and 568 patients were involved. D-RSBI had a pooled sensitivity of 0.84 and a pooled specificity of 0.87 which predicted weaning success. D-RSBI in the success group was significantly lower than the weaning failure group. Conclusion: D-RSBI is a sensitive and specific predictor for weaning outcomes in spite of the limitations and heterogeneity among the studies. Further studies focusing on particular disease are needed as well.