Auto-fluorescence of the bone and its use for delineation of bone necrosis

被引：38

作者：

Ristow, O. ^{[1
,2
]}

Pautke, C. ^{[2
,3
]}

机构：

[1] Heidelberg Univ, Dept Oral & Maxillofacial Surg, D-69120 Heidelberg, Germany

[2] Clin Oral & Maxillofacial & Plast Surg Med & Aest, Munich, Germany

[3] Univ Munich, Dept Oral & Maxillofacial Surg, Munich, Germany

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2014年 / 43卷 / 11期

关键词：

necrosis of the jaw; BRONJ; DRONJ; auto-fluorescence; therapy; bone; VELscope Vx; osteonecrosis; BISPHOSPHONATE-RELATED OSTEONECROSIS; RESECTION; JAWS;

D O I：

10.1016/j.ijom.2014.07.017

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a challenging complication of long-term bisphosphonate treatment. Currently, the drawback in the surgical management of BRONJ is the difficulty distinguishing between viable and necrotic bone. Intraoperative bone fluorescence induced by tetracyclines has been shown to be a valuable aid to overcome this problem. In this technical note we report the finding that viable bone is auto-fluorescent using the VELscope Vx fluorescence lamp. Necrotic bone shows an altered fluorescence pattern (pale or no fluorescence). Thus it is suggested that auto-fluorescence of bone might be of similar use during the surgical therapy of BRONJ.

引用

页码：1391 / 1393

页数：3

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