Novel antifungal diketopiperazine from marine fungus

被引：51
作者：
Byun, HG
Zhang, HP
Mochizuki, M
Adachi, K
Shizuri, Y
Lee, WJ
Kim, SK
机构：
[1] Pukyong Natl Univ, Dept Chem, Pusan 608737, South Korea
[2] Marine Biotechnol Inst Co Ltd, Shizuoka 4240037, Japan
[3] Pukyong Natl Univ, Dept Microbiol, Pusan 608737, South Korea
来源：
JOURNAL OF ANTIBIOTICS | 2003年 / 56卷 / 02期
关键词：
D O I：
10.7164/antibiotics.56.102
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Marine fungi producing antifungal compounds were screened against Pyricularia oryzae (P oryzae), and a metabolite of marine fungus M-3 isolated from laver (Porphyra yezoensis),showed potent activity. Novel diketopiperazine (1) was isolated from the culture extracts, and its structure was elucidated by spectroscopic methods. The MIC of 1 against P. oryzae was 0.36 muM.
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页码：102 / 106
页数：5
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