We report the case of a 72-year-old lady who presented to our institute with acute pancreatitis. Seven days later, she experienced an acute episode of chest pain associated with the pronounced electrocardiographic changes and elevated cardiac enzymes. Although subsequent coronary angiography was normal, a left ventriculogram demonstrated a marked area of apical akinesia and hyperkinesia of the basal left ventricular walls. We believe this to be the first case of pancreatitis induced takotsubo cardiomyopathy in the international literature. European Journal of Emergency Medicine 17:27-29 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.