Thiomethylation of amino alcohols using formaldehyde and hydrogen sulfide

被引：16

作者：

Akhmetova, V. R.

Nadyrgulova, G. R.

Tyumkina, T. V.

Starikova, Z. A.

Antipin, M. Yu.

Kunakova, R. V.

Dzhemilev, U. M.

机构：

[1] Russian Acad Sci, Inst Petr Chem & Catalysis, Ufa 450075, Bashkortostan, Russia

[2] Russian Acad Sci, AN Nesmeyanov Organomet Cpds Inst, Moscow, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 43卷 / 06期

关键词：

D O I：

10.1134/S1070428007060218

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three-component condensations of formaldehyde with hydrogen sulfide and hydroxylamine or amino alcohols at a ratio of 3:2:1 give 47-73% of N-hydroxy(or hydroxyalkyl)-1,3,5-dithiazinanes. The reactions of CH2O with H2S and hydroxylamine or alpha-amino alcohols at a ratio of 4:3:1 involve both amino and hydroxy groups, leading to the corresponding dithiazinanes. 4-Aminobutan-1-ol reacts with CH2O and H2S under analogous conditions only at the amino group to form 4-(1,3,5-dithiazinan-5-yl)butan-1-ol.

引用

页码：918 / 925

页数：8

共 28 条

[1]

ALEEV RS, 1988, DOKL AKAD NAUK SSSR+, V303, P873

[2] NEW CHIRAL HETEROCYCLES - 5-[(R)-(+)-1'-METHYLBENZYL]-1,3,5-DITHIAZINE AND 3,7-DI-[(R)-(+)-1'-METHYLBENZYL]-3,7-DIAZA-1,5-DITHIACYCLOOCTANE - CONFORMATIONAL STUDIES AND THEIR REACTIONS WITH BORANE [J].