Efficient Synthesis of 3,5,6,8-Tetrahydro-4H-thiopyrano[4′,3′:4,5]•thieno[2,3-d]pyrimidin-4-ones via an Iminophosphorane

被引：0
作者：
Li Wen-jing [1 ]
Liu Min [1 ]
Feng Ling-ling [1 ]
Ding Ming-wu [1 ]
机构：
[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China
来源：
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 2010年 / 26卷 / 01期
基金：
中国国家自然科学基金;
关键词：
3,5,6,8-Tetrahydro-4H-thiopyrano[4 ',3 ':4,5]thieno[2,3-d]pyrimidin-4-one; Aza-Wittig reaction; Carbodiimide; Isocyanate; IMIDAZOLIN-4-ONES; DERIVATIVES; RECEPTOR; ANALOGS; AGENTS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3,5,6,8-Tetrahydro-4H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-ones(7) were synthesized via the base catalytic reactions of amines or phenols with carbodiimides(5). which were obtained from the aza-Wittig reactions of iminophosphoranes(4) with aromatic isocyanates.
引用
收藏
页码：60 / 65
页数：6
相关论文
共 17 条
  • [1] SYNTHESIS OF NEW FUSED HETEROCYCLES BY ANNELATION OF THIOPYRANO[4',3'/4,5]THIENO[2,3-C]PYRIMIDINES
    AHMED, EK
    [J]. MONATSHEFTE FUR CHEMIE, 1995, 126 (8-9): : 953 - 959
  • [2] Fusion reactions of N-heterocyclic moieties to thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidines
    Ahmed, EK
    Frohlich, J
    Sauter, F
    [J]. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1996, 61 (01) : 147 - 154
  • [3] Novel synthesis of thieno[2,3-b]pyridine and substituted 2-thienylthiourea derivatives as antibiotic agents
    Al-Omran, F
    El-Khair, AA
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (06) : 909 - 914
  • [4] Chowdhury AZMS, 2001, HETEROCYCLES, V55, P1747
  • [5] Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors
    Dai, YJ
    Guo, Y
    Frey, RR
    Ji, ZQ
    Curtin, ML
    Ahmed, AA
    Albert, DH
    Arnold, L
    Arries, SS
    Barlozzari, T
    Bauch, JL
    Bouska, JJ
    Bousquet, PF
    Cunha, GA
    Glaser, KB
    Guo, J
    Li, JL
    Marcotte, PA
    Marsh, KC
    Moskey, MD
    Pease, LJ
    Stewart, KD
    Stoll, VS
    Tapang, P
    Wishart, N
    Davidsen, SK
    Michaelides, MR
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (19) : 6066 - 6083
  • [6] Ding M. W., 1997, WITTIG REACTION HETE, P73
  • [7] Ding MW, 2003, CHEM RES CHINESE U, V19, P302
  • [8] Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells
    Jennings, LD
    Kincaid, SL
    Wang, YND
    Krishnamurthy, G
    Beyer, CF
    McGinnis, JP
    Miranda, M
    Discafani, CM
    Rabindran, SK
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (21) : 4731 - 4735
  • [9] Exploration of a new type of antimalarial compounds based on febrifugine
    Kikuchi, Haruhisa
    Yamamoto, Keisuke
    Horoiwa, Seiko
    Hirai, Shingo
    Kasahara, Ryota
    Hariguchi, Norimitsu
    Matsumoto, Makoto
    Oshima, Yoshiteru
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (15) : 4698 - 4706
  • [10] Synthesis of a library of imidazolin-4-ones using poly(ethylene glycol) as soluble support
    Li, Hong-Xia
    Xie, Chang
    Ding, Ming-Wu
    Liu, Zu-Ming
    Yang, Guang-Fu
    [J]. SYNLETT, 2007, (14) : 2280 - 2282
12