Acetylcholine Receptor Stimulation for Cognitive Enhancement: Better the Devil You Know?

被引：12

作者：

Baxter, Mark G. ^{[1
,2
]}

Crimins, Johanna L. ^{[1
,2
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Neurosci, One Gustave L Levy Pl, New York, NY 10029 USA

[2] Icahn Sch Med Mt Sinai, Friedman Brain Inst, One Gustave L Levy Pl, New York, NY 10029 USA

来源：

NEURON | 2018年 / 98卷 / 06期

关键词：

PREFRONTAL CORTEX; MEMORY;

D O I：

10.1016/j.neuron.2018.06.018

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Drug treatments to improve memory focus on enhancing acetylcholine. However, Vijayraghavan and colleagues (2018) show that direct stimulation of the M1 muscarinic acetylcholine receptor adversely affected neuronal activity in prefrontal cortex related to working memory for behavioral rules.

引用

页码：1064 / 1066

页数：3

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