Emerging Fabrication Strategies of Hydrogels and Its Applications

被引：109
作者：
Ali, Fayaz [1 ,2 ]
Khan, Imran [3 ]
Chen, Jianmin [4 ]
Akhtar, Kalsoom [1 ]
Bakhsh, Esraa M. [1 ]
Khan, Sher Bahadar [1 ,2 ]
机构：
[1] King Abdulaziz Univ, Dept Chem, POB 80203, Jeddah 21589, Saudi Arabia
[2] King Abdulaziz Univ, Ctr Excellence Adv Mat Res, POB 80203, Jeddah 21589, Saudi Arabia
[3] Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Avenida Wai Long, Taipa 999078, Madhya Pradesh, Peoples R China
[4] Putian Univ, Sch Pharm & Med Technol, 1133 Xueyuan Zhong Jie, Putian 351100, Peoples R China
来源：
GELS | 2022年 / 8卷 / 04期
关键词：
hydrogels; natural polymers; drug delivery; IN-SITU GEL; INDUCED CROSS-LINKING; NANOPARTICLE-EMBEDDED HYDROGEL; CONTROLLED DRUG-DELIVERY; CHITOSAN-BASED HYDROGEL; SELF-HEALING HYDROGEL; CONTROLLED-RELEASE; NASAL DELIVERY; THERMOSENSITIVE HYDROGEL; COMPOSITE HYDROGEL;
D O I：
10.3390/gels8040205
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Recently, hydrogels have been investigated for the controlled release of bioactive molecules, such as for living cell encapsulation and matrices. Due to their remote controllability and quick response, hydrogels are widely used for various applications, including drug delivery. The rate and extent to which the drugs reach their targets are highly dependent on the carriers used in drug delivery systems; therefore the demand for biodegradable and intelligent carriers is progressively increasing. The biodegradable nature of hydrogel has created much interest for its use in drug delivery systems. The first part of this review focuses on emerging fabrication strategies of hydrogel, including physical and chemical cross-linking, as well as radiation cross-linking. The second part describes the applications of hydrogels in various fields, including drug delivery systems. In the end, an overview of the application of hydrogels prepared from several natural polymers in drug delivery is presented.
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页数：39
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