Basal cell carcinoma with matrical differentiation:: a case study with analysis of β-catenin

被引：22
作者：
Haskell, HD
Haynes, HA
McKee, PH
Redston, M
Granter, SR
Lazar, AJF
机构：
[1] Harvard Univ, Sch Med, Boston, MA USA
[2] Brigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Pathol, Div Dermatopathol, Boston, MA 02115 USA
来源：
JOURNAL OF CUTANEOUS PATHOLOGY | 2005年 / 32卷 / 03期
关键词：
D O I：
10.1111/j.0303-6987.2005.00301.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Matrical differentiation in basal cell carcinoma (BCC) is rare. Only nine cases have been described that showed typical diagnostic features of BCC, in addition to shadow cells indicating hair-matrix differentiation.(1-5) These cases often present a diagnostic challenge due to confusion with pilomatrixoma or pilomatrix carcinoma. We present a case of BCC with matrical differentiation in a 78-year-old man. Immunohistochemical and molecular methods are used to differentiate this lesion from benign or malignant forms of pilomatrixoma.
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页码：245 / 250
页数：6
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