Synthesis of α,α-difluorobenzoyl oxygen heterocycles via the radical reaction of 2-iodo-2,2-difluoroacetophenones with unsaturated acids or unsaturated alcohols

被引：18

作者：

Chen, Heng ^{[1
]}

Wang, Jiexiong ^{[1
]}

Wu, Jingjing ^{[1
,2
]}

Kuang, Yujia ^{[1
]}

Wu, Fanhong ^{[1
]}

机构：

[1] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2017年 / 200卷

基金：

中国国家自然科学基金;

关键词：

alpha-alpha-Difluorobenzoyl oxygen heterocycle; 2-Iodo-2,2-difluoroacetophenone; Radical addition; Unsaturated acids; Unsaturated alcohols; CATALYZED ALPHA-ARYLATION; IODODIFLUOROMETHYL KETONES; PERFLUOROALKYL IODIDES; GAMMA-BUTYROLACTONES; COPPER CATALYST; ARYL BROMIDES; ALKENES; DERIVATIVES; ALKYNES; ARENES;

D O I：

10.1016/j.jfluchem.2017.06.003

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A convenient and facile method for the direct synthesis of a,a-difluorobenzoyl lactones or cyclic ethers via the radical cyclization reaction of 2-iodo-2,2-difluoroacetophenone with unsaturated acids or alcohols was reported.

引用

页码：41 / 46

页数：6

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