Immobilization of biomolecules on the surface of inorganic nanoparticles for biomedical applications

被引：50
作者：
Xing, Zhi-Cai [1 ]
Chang, Yongmin [2 ]
Kang, Inn-Kyu [1 ]
机构：
[1] Kyungpook Natl Univ, Dept Polymer Sci & Engn, Taegu 702701, South Korea
[2] Kyungpook Natl Univ, Dept Diagnost Radiol, Taegu 700422, South Korea
来源：
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS | 2010年 / 11卷 / 01期
关键词：
inorganic nanoparticles; immobilization; biomolecule; biomedical application; WALLED CARBON NANOTUBES; LAYERED DOUBLE HYDROXIDES; MAGNETIC NANOPARTICLES; QUANTUM DOTS; PANCREATIC-CANCER; SILICA NANOPARTICLES; GOLD NANOPARTICLES; IN-VITRO; DELIVERY; CELLS;
D O I：
10.1088/1468-6996/11/1/014101
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Various inorganic nanoparticles have been used for drug delivery, magnetic resonance and fluorescence imaging, and cell targeting owing to their unique properties, such as large surface area and efficient contrasting effect. In this review, we focus on the surface functionalization of inorganic nanoparticles via immobilization of biomolecules and the corresponding surface interactions with biocomponents. Applications of surface-modified inorganic nanoparticles in biomedical fields are also outlined.
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页数：17
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