Primary intramedullary melanoma of lumbar spinal cord: A case report

被引:1
作者
Sun, Le-Dong [1 ]
Chu, Xin [1 ]
Xu, Li [1 ]
Fan, Xiu-Zhen [1 ]
Qian, Yi [2 ]
Zuo, Da-Ming [3 ]
机构
[1] Southern Med Univ, Dept Dermatol, Affiliated Hosp 5, Guangzhou 510900, Guangdong, Peoples R China
[2] Southern Med Univ, Affiliated Hosp 5, 566 Congcheng Ave, Guangzhou 510900, Guangdong, Peoples R China
[3] Southern Med Univ, Dept Med Lab, Guangzhou 510515, Guangdong, Peoples R China
关键词
Intramedullary melanoma; Spinal cord; Lumbar; Magnetic resonance imaging; Histopathological examination; Immunohistochemical staining; Case report;
D O I
10.12998/wjcc.v9.i10.2352
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Primary intramedullary melanoma is a very rare tumor, most frequently occurring in the cervical and thoracic spinal cord. CASE SUMMARY We present a rare case in which the primary intramedullary melanoma was located in the lumbar spine. A 56-year-old man complained of progressive intermittent pain in the lumbar area. Thoracic magnetic resonance imaging showed a spinal intramedullary tumor between the L3 and S1 levels. The tumor was resected entirely, and the diagnosis of malignant melanoma was confirmed by histopathology. CONCLUSION Primary melanoma of the spinal cord, particularly intramedullary localization, has rarely been reported in the previous literature. We describe a primary malignant melanoma of the lumbar spinal cord and discuss the challenges associated with the diagnosis.
引用
收藏
页码:2352 / 2356
页数:5
相关论文
共 11 条
[1]   The Molecular Pathology of Melanoma: An Integrated Taxonomy of Melanocytic Neoplasia [J].
Bastian, Boris C. .
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 9, 2014, 9 :239-271
[2]   Epithelioid Schwannomas An Analysis of 58 Cases Including Atypical Variants [J].
Hart, Jesse ;
Gardner, Jerad M. ;
Edgar, Mark ;
Weiss, Sharon W. .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2016, 40 (05) :704-713
[3]   MALIGNANT-MELANOMA AND CENTRAL NERVOUS-SYSTEM - GUIDE FOR CLASSIFICATION BASED ON CLINICAL FINDINGS [J].
HAYWARD, RD .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1976, 39 (06) :526-530
[4]   Primary spinal melanoma of extramedullary origin: a report of three cases and systematic review of the literature [J].
Q-Y Liu ;
A-M Liu ;
H-G Li ;
Y-B Guan .
Spinal Cord Series and Cases, 1 (1)
[5]   Primary melanocytic neoplasms of the central nervous system [J].
Liubinas, Simon V. ;
Maartens, Nicholas ;
Drummond, Katharine J. .
JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (10) :1227-1232
[6]   Insights into Differentiation of Melanocytes from Human Stem Cells and Their Relevance for Melanoma Treatment [J].
Mirea, Madalina A. ;
Eckensperger, Stefan ;
Hengstschlaeger, Markus ;
Mikula, Mario .
CANCERS, 2020, 12 (09) :1-19
[7]   Spinal meningeal melanocytoma: A rare meningeal tumor [J].
Shanthi, Vissa ;
Ramakrishna, B. A. ;
Bheemaraju, Vydehi Venkata ;
Rao, Nandam Mohan ;
Athota, Venkata Ramana Murthy .
ANNALS OF INDIAN ACADEMY OF NEUROLOGY, 2010, 13 (04) :308-310
[8]   Primary Spinal Cord Melanoma of Intradural Extramedullary Origin [J].
Sharma, Ashish ;
Sinha, Virendra Deo .
JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE, 2019, 10 (03) :522-525
[9]   MENINGEAL MELANOCYTOMA - MAGNETIC-RESONANCE-IMAGING CHARACTERISTICS AND PATHOLOGICAL FEATURES - CASE-REPORT [J].
UEMATSU, Y ;
YUKAWA, S ;
YOKOTE, H ;
ITAKURA, T ;
HAYASHI, S ;
KOMAI, N .
JOURNAL OF NEUROSURGERY, 1992, 76 (04) :705-709
[10]   Expression of microphthalmia transcription factor, S100 protein, and HMB-45 in malignant melanoma and pigmented nevi [J].
Xia, Jianxin ;
Wang, Yanlong ;
Li, Fuqiu ;
Wang, Jinfeng ;
Mu, Yan ;
Mei, Xianglin ;
Li, Xue ;
Zhu, Wenjing ;
Jin, Xianhua ;
Yu, Kai .
BIOMEDICAL REPORTS, 2016, 5 (03) :327-331