A randomized, double-blind, parallel-group, placebo-controlled Phase 3 trial to evaluate efficacy and safety of ocrelizumab in PPMS

被引：0
|
作者：
Montalban, Xavier [1 ]
Hemmer, Bernhard [2 ,3 ]
Rammohan, Kottil W. [4 ]
Giovannoni, Gavin [5 ]
De Seze, Jerome [6 ]
Bar-Or, Amit [7 ]
Arnold, Douglas L. [7 ,8 ]
Sauter, Annette [9 ]
Masterman, Donna [10 ]
Fontoura, Paulo [9 ]
Chin, Peter [11 ]
Garren, Hideki [9 ]
Wolinsky, Jerry S. [12 ]
机构：
[1] Hosp Vall dHebron Univ, Barcelona, Spain
[2] Tech Univ Munich, D-80290 Munich, Germany
[3] Munich Cluster Syst Neurol SyNergy, Munich, Germany
[4] Univ Miami, Miami, FL USA
[5] Queen Mary Univ London, London, England
[6] Univ Hosp Strasbourg, Strasbourg, France
[7] McGill Univ, Montreal, PQ, Canada
[8] NeuroRx Res, Montreal, PQ, Canada
[9] F Hoffmann La Roche & Co Ltd, Basel, Switzerland
[10] Genentech Inc, San Francisco, CA 94080 USA
[11] Genentech Inc, 460 Point San Bruno Blvd, San Francisco, CA 94080 USA
[12] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA
来源：
MULTIPLE SCLEROSIS JOURNAL | 2016年 / 22卷
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
P023
引用
收藏
页码：17 / 17
页数：1
相关论文
共 50 条
  • [31] CASCADE: a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of tezepelumab on airway inflammation in patients with uncontrolled asthma
    Emson, Claire
    Diver, Sarah
    Chachi, Latifa
    Megally, Ayman
    Small, Cherrie
    Downie, John
    Parnes, Jane R.
    Bowen, Karin
    Colice, Gene
    Brightling, Chris E.
    RESPIRATORY RESEARCH, 2020, 21 (01)
  • [32] A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Sirukumab in the Treatment of Giant Cell Arteritis
    Schmidt, Wolfgang A.
    Dasgupta, Bhaskar
    Luqmani, Raashid
    Unizony, Sebastian H.
    Blockmans, Daniel
    Lai, Zhihong
    Kurrasch, Regina H.
    Lazic, Ivana
    Brown, Kurt
    Rao, Ravi
    RHEUMATOLOGY AND THERAPY, 2020, 7 (04) : 793 - 810
  • [33] A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Sirukumab in the Treatment of Giant Cell Arteritis
    Wolfgang A. Schmidt
    Bhaskar Dasgupta
    Raashid Luqmani
    Sebastian H. Unizony
    Daniel Blockmans
    Zhihong Lai
    Regina H. Kurrasch
    Ivana Lazic
    Kurt Brown
    Ravi Rao
    Rheumatology and Therapy, 2020, 7 : 793 - 810
  • [34] Phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group study of ustekinumab in patients with Takayasu arteritis
    Yoshifuji, Hajime
    Ishii, Tomonori
    Ohashi, Hiroki
    Yoshizawa, Katsunori
    Mihoya, Maki
    Nishikawa, Kazuko
    Nakaoka, Yoshikazu
    RHEUMATOLOGY ADVANCES IN PRACTICE, 2025, 9 (02)
  • [35] Efficacy and Safety of Dupilumab in Patients From China With Persistent Asthma: A Subgroup Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study
    Zhang, Q.
    Zhong, N.
    Fang, H.
    Zhu, S.
    Wang, Z.
    Zhao, L.
    Laws, E.
    Mannent, L.
    Wang, Y.
    Li, V.
    Li, A.
    Hu, C.
    Lederer, D. J.
    Abdulai, R. M.
    Robinson, L.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207
  • [36] Ebronucimab in Chinese patients with hypercholesterolemia---A randomized double-blind placebo-controlled phase 3 trial to evaluate the efficacy and safety of ebronucimab
    Zhang, Yanyan
    Pei, Zhaohui
    Chen, Beijian
    Qu, Yanling
    Dong, Xiaolin
    Yu, Binge
    Wang, Guoqin
    Xu, Fang
    Lu, Dongmei
    He, Zhimei
    Chen, Benchao
    Ma, Lei
    Wang, Max
    Li, Baiyong
    Xia, Michelle
    Zheng, Bo
    Huo, Yong
    PHARMACOLOGICAL RESEARCH, 2024, 207
  • [37] Efficacy of Zhengtian Pill for migraine prophylaxis: A randomized, multicenter, double-blind, placebo-controlled, parallel-group study
    Cao, Kegang
    Yu, Lihua
    Gao, Ying
    Fan, Yongping
    Zhao, Jianjun
    Zhang, Xuezhi
    Xie, Wei
    Yang, Wenming
    Dong, Mengjiu
    Li, Tao
    Qiao, Xiangyang
    EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE, 2014, 6 (03) : 259 - 267
  • [38] CARDINALS: a phase 2, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of utreloxastat (PTC857) in patients with amyotrophic lateral sclerosis
    Katz, Jonathan S.
    Vu, Tuan
    Chio, Adriano
    McDermott, Chris
    Devos, David
    Gordon, Greg
    Johnston, Mayzie
    Maier, James
    Trimmer, Jeff
    Tansy, Aaron
    Shefner, Jeremy M.
    MUSCLE & NERVE, 2023, 68 : S61 - S62
  • [39] Efficacy and safety of Qiangli Dingxuan tablet combined with amlodipine besylate for essential hypertension: a randomized, double-blind, placebo-controlled, parallel-group, multicenter trial
    Lin, Jianguo
    Wang, Qingqing
    Zhong, Dongsheng
    Zhang, Jinju
    Yuan, Tianhui
    Wu, Hui
    Li, Bin
    Li, Shuangdi
    Xie, Xiaoliu
    An, Dongqing
    Deng, Yue
    Xian, Shaoxiang
    Xiong, Xingjiang
    Yao, Kuiwu
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [40] A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial of Extract Sceletium tortuosum (Zembrin) in Healthy Adults
    Nell, Haylene
    Siebert, Mirna
    Chellan, Pashini
    Gericke, Nigel
    JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2013, 19 (11) : 898 - 904
12345