Synthesis and biological evaluation of some novel schiff's bases from 1,2,4-triazole

被引：27

作者：

Ye, Xiao-Xia

Chen, Zhen-Fei

Zhang, An-Jiang

Zhang, Li-Xue ^{[1
]}

机构：

[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325027, Peoples R China

[2] Wenzhou Med Coll, Wenzhou 325035, Peoples R China

来源：

MOLECULES | 2007年 / 12卷 / 06期

关键词：

schiff s bases; glucoheptonic acid residue; 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione; plant growth regulation;

D O I：

10.3390/12061202

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have synthesized a number of novel Schiff's bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonichexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the tide compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, H-1-NMR, C-13-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities.

引用

页码：1202 / 1209

页数：8

共 12 条

[1]

[Anonymous], FARMACO

[2]

Chaha V. K., 1998, J PHYTOL RES, V11, P201

[3]

ERNST H, 1982, Patent No. 2078212

[4] Synthesis and studies on some new fluorine containing triazolothiadiazines as possible antibacterial, antifungal and anticancer agents [J].

Holla, B. Shivarama ;

Rao, B. Sooryanarayana ;

Sarojini, B. K. ;

Akberali, P. M. ;

Kumari, N. Suchetha .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 41 (05) :657-663

[5] Studies on nitrophenylfuran derivatives -: Part XII.: Synthesis, characterization, antibacterial and antiviral activities of some nitrophenylfurfurylidene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines [J].

Holla, BS ;

Akberali, PM ;

Shivananda, MK .

FARMACO, 2001, 56 (12) :919-927

[6]

Holla BS, 2000, FARMACO, V55, P338

[7]

Hui XP, 2005, CHINESE J ORG CHEM, V25, P700

[8]

Nadkarni BA, 2001, ARZNEIMITTELFORSCH, V51, P569

[9] Synthesis of thiazole, oxazole and heterocyclic ring-substituted 1,2-dioxanes [J].

Sakata, M ;

Shirakawa, Y ;

Kamata, N ;

Sakaguchi, Y ;

Nishino, H ;

Ouyang, J ;

Kurosawa, K .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2000, 37 (02) :269-274

[10]

SHI HJ, 1998, SYNTHETIC COMMUN, V28, P3937

← 1 2 →