Spectral attenuation of brain and retina tissues in the near-infrared range measured using a fiber-based supercontinuum device

被引:5
作者
Eduardo Saldana-Diaz, Jose [1 ,2 ]
Jarabo, Sebastian [1 ]
Javier Salgado-Remacha, Francisco [1 ]
Perdices, Lorena [3 ]
Pinilla, Isabel [4 ,5 ,6 ]
Sanchez-Cano, Ana [1 ,6 ]
机构
[1] Univ Zaragoza, Dept Fis Aplicada, Pedro Cerbuna 12, E-50009 Zaragoza, Spain
[2] Univ Nacl Huancavel, Fac Ciencias & Ingn, Dept Acad Ciencias Basicas, Huancavelica, Peru
[3] IACS, Avda San Juan Bosco 13, E-50009 Zaragoza, Spain
[4] Univ Zaragoza, Dept Cirugia Ginecol & Obstet, Pedro Cerbuna 12, E-50009 Zaragoza, Spain
[5] Hosp Clin Univ Lozano Blesa, Oftalmol, Ave San Juan Bosco 15, E-50009 Zaragoza, Spain
[6] IIS Aragon, Avda San Juan Bosco 13, E-50009 Zaragoza, Spain
关键词
fiber lasers; supercontinuum devices; spectral attenuation; biological tissues; IN-VIVO; MOUSE-BRAIN; MICROSCOPY;
D O I
10.1002/jbio.201600292
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A novel setup for the efficient constant optical measurements of biological tissues in the near infrared is presented. The system combines the use of a fiber-based supercontinuum source with a simple optics fiber collimator. This configuration allows a wide spectral range of measurement and, at the same time, can efficiently filter the straightforward transmitted light while avoiding scattered light. As a performance example, the optical characterization of rat brain and retina tissues are shown. The attenuation coefficient for both tissues in the near infrared region is also obtained. This technique could be applied in clinical research as a non-invasive method with several potential practical applications. [GRAPHICS] .
引用
收藏
页码:1105 / 1109
页数:5
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