A competitive coordination-based CeO2 nanowire-DNA nanosensor: fast and selective detection of hydrogen peroxide in living cells and in vivo

被引:42
作者
Gao, Wen [1 ]
Wei, Xueping [1 ]
Wang, Xuejun [2 ]
Cui, Guanwei [1 ]
Liu, Zhenhua [1 ]
Tang, Bo [1 ]
机构
[1] Shandong Normal Univ, Shandong Prov Key Lab Clean Prod Fine Chem, Key Lab Mol & Nano Probes,Minist Educ,Coll Chem, Collaborat Innovat Ctr Functionalized Probes Chem, Jinan 250014, Peoples R China
[2] Shandong Ctr Dis Control & Prevent, Jinan 250014, Peoples R China
基金
中国国家自然科学基金;
关键词
NANOPARTICLES; NANOPROBE; COMPLEXES; OXIDATION; NANORODS; OXYGEN; STATE;
D O I
10.1039/c6cc00112b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A competitive coordination-based hydrogen peroxide (H2O2) nanosensor is constructed by the assembly of FAM-tagged single-strand (ss) DNA on cerium oxide nanowires (CeO2 NWs). This fluorescent nanosensor is capable of rapidly and selectively tracking H2O2 within living cells, as well as directly visualizing H2O2 generated by wound-induced oxidative damage in zebrafish larvae.
引用
收藏
页码:3643 / 3646
页数:4
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