Consistency of Signal Intensity and T2*in Frozen Ex Vivo Heart Muscle, Kidney, and Liver Tissue

被引：18

作者：

Kaye, Elena A. ^{[1
,2
]}

Josan, Sonal ^{[2
]}

Lu, Aiming ^{[3
]}

Rosenberg, Jarrett ^{[2
]}

Daniel, Bruce L. ^{[2
]}

Pauly, Kim Butts ^{[2
]}

机构：

[1] Stanford Univ, Dept Elect Engn, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Radiol, Stanford, CA 94305 USA

[3] Univ Illinois, Ctr MR Res, Chicago, IL USA

来源：

JOURNAL OF MAGNETIC RESONANCE IMAGING | 2010年 / 31卷 / 03期

关键词：

cryoablation; T2*; hydration water; frozen tissue; MAGNETIC-RESONANCE; BIOLOGICAL-SYSTEMS; RELAXATION-TIMES; EDDY CURRENTS; RF PULSES; WATER; TEMPERATURE; CRYOSURGERY; PROTON; NMR;

D O I：

10.1002/jmri.22029

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: To investigate tissue dependence of the MRI-based thermometry in frozen tissue by quantification and comparison of signal intensity and T2* of ex vivo frozen tissue of three different types: heart muscle, kidney, and liver. Materials and Methods: Tissue samples were frozen and imaged on a 0.5 Tesla MRI scanner with ultrashort echo time (UTE) sequence. Signal intensity and T2* were determined as the temperature of the tissue samples was decreased from room temperature to approximately -40 degrees C. Statistical analysis was performed for (-20 degrees C, -5 degrees C) temperature interval. Results: The findings of this study demonstrate that signal intensity and T2* are consistent across three types of tissue for (-20 degrees C, -5 degrees C) temperature interval. Conclusion: Both parameters can be used to calculate a single temperature calibration curve for all three types of tissue and potentially in the future serve as a foundation for tissue-independent MRI-based thermometry.

引用

页码：719 / 724

页数：6

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