Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis

被引：7

作者：

Nnaji, Chukwudi A. ^{[1
,2
]}

Wiysonge, Charles S. ^{[1
,2
,3
,4
]}

Adamu, Abdu A. ^{[2
,3
]}

Lesosky, Maia ^{[1
]}

Mahomed, Hassan ^{[5
,6
]}

Ndwandwe, Duduzile ^{[2
]}

机构：

[1] Univ Cape Town, Sch Publ Hlth & Family Med, Div Epidemiol & Biostat, ZA-7925 Cape Town, South Africa

[2] South African Med Res Council, Cochrane South Africa, ZA-7501 Cape Town, South Africa

[3] Stellenbosch Univ, Dept Global Hlth, Div Epidemiol & Biostat, ZA-7505 Cape Town, South Africa

[4] South African Med Res Council, HIV & Other Infect Dis Res Unit, ZA-7501 Cape Town, South Africa

[5] Western Cape Prov Dept Hlth, ZA-8000 Cape Town, South Africa

[6] Stellenbosch Univ, Dept Global Hlth, Div Hlth Syst & Publ Hlth, ZA-7505 Cape Town, South Africa

来源：

VACCINES | 2022年 / 10卷 / 05期

基金：

新加坡国家研究基金会; 英国医学研究理事会;

关键词：

missed opportunities for vaccination; vaccination; immunisation; children; primary health care; quality improvement; South Africa; COST-EFFECTIVENESS; IMMUNIZATION; BENEFITS; VACCINES; COVID-19;

D O I：

10.3390/vaccines10050785

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Despite the substantial efforts at ensuring universal access to routine immunisation services among children in South Africa, major gaps in immunisation coverage remain. This study assessed the magnitude of missed opportunities for vaccination (MOV) and associated factors among children aged 0-23 months attending primary health care (PHC) facilities in Cape Town. We used multilevel binomial logistic regression models to explore individual and contextual factors associated with MOV, with children aged 0-23 months at Level 1, nested within PHC facilities (Level 2). A total of 674 children and their caregivers were enrolled. MOV prevalence was 14.1%, ranging from 9.1% to 18.9% across sub-districts. Dose-specific MOV prevalence was highest for the second dose of measles vaccine (9.5%) and lowest for the first dose of rotavirus vaccine (0.6%). The likelihood of a child experiencing MOV was significantly associated with caregivers' low level of education (Odds ratio (OR) = 3.53, 95% credible interval (CrI): 1.13-11.03), recent receipt of immunisation messages (OR = 0.46, 95%CrI: 0.25-0.87), shared immunisation decision making by both parents (OR = 0.21, 95%CrI: 0.07-0.62) and health facility staff number (OR = 0.18, 95%CrI: 0.06-0.61). The burden of MOV among children in Cape Town is influenced by individual and contextual factors, which provide important opportunities for quality improvement and broader strategies to improve routine immunisation service delivery.

引用

页数：18

共 62 条

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