Rapid microwave-assisted synthesis of phenyl ethers under mildly basic and nonaqueous conditions

被引：24

作者：

Sarju, J

Danks, TN

Wagner, G ^{[1
]}

机构：

[1] Univ Surrey, SBMS, Div Chem, Guildford GU2 7XH, Surrey, England

[2] Oratory Sch, Reading RG8 0PJ, Berks, England

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 41期

关键词：

microwave irradiation; ether synthesis; O-alkylation; potassium carbonate;

D O I：

10.1016/j.tetlet.2004.08.087

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild method for O-alkylation of phenols has been developed using stoichiometric amounts of K2CO3 as a base and microwave irradiation. The method is suitable for substrates that are sensitive towards strong bases or hydrolysis, or difficult to extract from an aqueous medium. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：7675 / 7677

页数：3

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