Primary malignant melanoma of the larynx: A case report and literature review

被引：19

作者：

Terada, Tomonori ^{[1
]}

Saeki, Nobuo ^{[1
]}

Toh, Kunichika ^{[1
]}

Uwa, Nobuhiro ^{[1
]}

Sagawa, Kosuke ^{[1
]}

Mouri, Takeshi ^{[1
]}

Sakagami, Masafumi ^{[1
]}

机构：

[1] Hyogo Med Univ, Dept Otolaryngol, Nishinomiya, Hyogo 6638501, Japan

来源：

AURIS NASUS LARYNX | 2007年 / 34卷 / 01期

关键词：

malignant melanoma; larynx; head and neck;

D O I：

10.1016/j.anl.2006.09.027

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

A 56-year-old Japanese man presented with hoarseness and left sided neck swelling in June 2003. Endoscopy showed an irregular tumor extending from the anterior commissure to the left ventricle with dark pigmentation. A biopsy showed malignant melanoma. A total laryngectomy with left radical neck dissection was performed in July 2003, followed by chemohormonal therapy and radiotherapy to the neck. Multiple bone metastases were diagnosed in May 2004, and the patient died with disseminated disease in April 2005, 21 months after initial treatment. The medical literature on laryngeal malignant melanoma was reviewed, and suggested a very poor prognosis despite therapy with surgery, radiotherapy, and chemotherapy. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：105 / 110

页数：6

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