Spinal cord ependymoma: a review of the literature and case series of ten patients

被引:65
|
作者
Celano, Emma [1 ]
Salehani, Arsalaan [1 ]
Malcolm, James G. [1 ]
Reinertsen, Erik [1 ,2 ]
Hadjipanayis, Constantinos G. [3 ]
机构
[1] Emory Univ, Sch Med, Atlanta, GA USA
[2] Georgia Inst Technol, Dept Biomed Engn, Atlanta, GA 30332 USA
[3] Icahn Sch Med Mt Sinai, Mt Sinai Beth Israel Philips Ambulatory Care Ctr, Dept Neurosurg, 10 Union Sq,5th Floor,Suite 5E, New York, NY 10003 USA
关键词
Spinal cord; Ependymoma; Tumor; Review; Case series; LONG-TERM OUTCOMES; SURGICAL-TREATMENT; INTRAMEDULLARY EPENDYMOMAS; MYXOPAPILLARY EPENDYMOMA; CLINICAL PRESENTATION; RADIATION-THERAPY; FILUM TERMINALE; RESECTION; TUMORS; SUBEPENDYMOMA;
D O I
10.1007/s11060-016-2135-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Spinal cord ependymoma (SCE) is a rare tumor that is most commonly low-grade. Complete surgical resection has been established as first-line treatment and can be curative. However, SCEs tend to recur when complete tumor resection is not possible. Evidence supporting the use of adjuvant radiation and chemotherapy is not definitive. We review the most recent literature on SCE covering a comprehensive range of topics spanning the biology, presentation, clinical management, and outcomes. In addition, we present a case series of ten SCE patients with the goal of contributing to existing knowledge of this rare disease.
引用
收藏
页码:377 / 386
页数:10
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