Influence of nanoscale surface topography on protein adsorption and cellular response

被引：526
作者：
Lord, Megan S. [3 ]
Foss, Morten [1 ,2 ]
Besenbacher, Flemming [1 ,2 ]
机构：
[1] Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, DK-8000 Aarhus C, Denmark
[2] Aarhus Univ, Dept Phys & Astron, DK-8000 Aarhus C, Denmark
[3] Univ New S Wales, Grad Sch Biomed Engn, Sydney, NSW 2052, Australia
来源：
NANO TODAY | 2010年 / 5卷 / 01期
关键词：
Nanoscale surface topography (nanotopography); Protein adsorption; Cellular response; SILICA NANOPARTICULATE COATINGS; ENHANCED OSTEOBLAST ADHESION; OSTEOPROGENITOR RESPONSE; NANOMETER-SCALE; IMPRINT LITHOGRAPHY; FIBROBLAST RESPONSE; CONTACT GUIDANCE; THIN-FILMS; CELLS; NANOTOPOGRAPHY;
D O I：
10.1016/j.nantod.2010.01.001
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The nanoscale surface topography of artificial materials is known to play a significant role in interactions with biological, systems such as proteins and cells. A detailed understanding, and ultimately control, of these interactions is therefore of utmost importance in areas such as cell culture technology, biosensing and medical device development. We briefly review different methods to synthesise and fabricate surfaces with well-defined nanoscale topography, and discuss how such nanostructured surfaces can be used as model systems in protein and cellular assays. Finally, an outlook of possible future in vitro and in vivo developments is provided. (C) 2010 Published by Elsevier Ltd.
引用
收藏
页码：66 / 78
页数：13
相关论文
共 111 条
[1]   Topography and surface composition of thin films of blends of polystyrene with brominated polystyrenes: Effects of varying the degree of bromination and annealing [J].
Affrossman, S ;
O'Neill, SA ;
Stamm, M .
MACROMOLECULES, 1998, 31 (18) :6280-6288
[2]   Surface topography and composition of deuterated polystyrene-poly(bromostyrene) blends [J].
Affrossman, S ;
Henn, G ;
ONeill, SA ;
Pethrick, RA ;
Stamm, M .
MACROMOLECULES, 1996, 29 (14) :5010-5016
[3]   Micro and nano-structured surfaces [J].
Barbucci, R ;
Pasqui, D ;
Wirsen, A ;
Affrossman, S ;
Curtis, A ;
Tetta, C .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2003, 14 (08) :721-725
[4]   Endothelial cell response to narrow diameter nylon tubes exhibiting internal nanotopography [J].
Berry, C. ;
McCloy, D. ;
Affrossman, S. .
CURRENT NANOSCIENCE, 2008, 4 (02) :219-223
[5]   The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading [J].
Biggs, M. J. P. ;
Richards, R. G. ;
Gadegaard, N. ;
Wilkinson, C. D. W. ;
Dalby, M. J. .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2007, 18 (02) :399-404
[6]   The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+enriched skeletal stem cells [J].
Biggs, Manus J. P. ;
Richards, R. Geoff ;
Gadegaard, NikolaJ ;
Wilkinson, Chris D. W. ;
Oreffo, Richard O. C. ;
Dalby, Matthew J. .
BIOMATERIALS, 2009, 30 (28) :5094-5103
[7]   Simultaneous investigation of the influence of topography and charge on protein adsorption using artificial nanopatterns [J].
Blanco, E. Macarena ;
Horton, Michael A. ;
Mesquida, Patrick .
LANGMUIR, 2008, 24 (06) :2284-2287
[8]   Surface-induced microphase separation in spin-cast ultrathin diblock copolymer films on silicon substrate before and after annealing [J].
Buck, E ;
Fuhrmann, J .
MACROMOLECULES, 2001, 34 (07) :2172-2178
[9]   Endothelization and adherence of leucocytes to nanostructured surfaces [J].
Buttiglieri, S ;
Pasqui, D ;
Migliori, M ;
Johnstone, H ;
Affrossman, S ;
Sereni, L ;
Wratten, ML ;
Barbucci, R ;
Tetta, C ;
Camussi, G .
BIOMATERIALS, 2003, 24 (16) :2731-2738
[10]   Control of power law scaling in the growth of silicon nanocolumn pseudo-regular arrays deposited by glancing angle deposition [J].
Buzea, C ;
Beydaghyan, G ;
Elliott, C ;
Robbie, K .
NANOTECHNOLOGY, 2005, 16 (10) :1986-1992
12345678910