Nanoceria: a Potential Therapeutic for Dry AMD

被引：20
作者：
Cai, Xue [1 ]
McGinnis, James F. [1 ,2 ]
机构：
[1] Univ Oklahoma, Hlth Sci Ctr, Dept Ophthalmol, Dean McGee Eye Inst, 608 Stanton L Young Blvd, Oklahoma City, OK 73104 USA
[2] Univ Oklahoma, Hlth Sci Ctr, Dept Ophthalmol, Dean McGee Eye Inst,Dept Cell Biol,Oklahoma Ctr N, Oklahoma City, OK 73104 USA
来源：
RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY | 2016年 / 854卷
关键词：
Dry AMD; Drusen; RPE; Animal models; Therapeutic strategies; Nanoceria; RETINAL-PIGMENT EPITHELIUM; MACULAR DEGENERATION; INTRAVITREAL INJECTION; GEOGRAPHIC ATROPHY; TUBBY MICE; ACTIVATION; AUTOPHAGY; MODEL; NANOPARTICLES; PROTECTION;
D O I：
10.1007/978-3-319-17121-0_16
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Age-related macular degeneration (AMD) is the leading cause of blinding diseases. The "dry" form of AMD is the most common form of AMD. In contrast to the treatable neovascular (wet) AMD, no effective treatment is available for dry AMD. In this review, we summarize the animal models and therapeutic strategies for dry AMD. The novel candidates as potential treatment targets and the potential effectiveness of nanoceria as a treatment of dry AMD are also discussed.
引用
收藏
页码：111 / 118
页数：8
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