Diffusion and fate of intramuscularly injected human rabies immune globulin

被引：20
|
作者：
Saesow, N
Chaiwatanarat, T
Mitmoonpitak, C
Wilde, H
机构：
[1] Chulalongkorn Univ Hosp, Dept Radiol, Div Nucl Med, Bangkok 10330, Thailand
[2] Thai Red Cross Soc, Queen Saovabha Mem Inst, Bangkok 10330, Thailand
来源：
ACTA TROPICA | 2000年 / 76卷 / 03期
关键词：
rabies; rabies immune globulin; absorption and diffusion of rabies immune globulin;
D O I：
10.1016/S0001-706X(00)00107-8
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The importance of rabies immune globulin (RIG) in postexposure rabies treatment is well known and it has been emphasized that the local injection into the animal bite sites is crucial. This preliminary study used a radioisotope tracer that allows following the fate of human rabies immune globulin (HRIG) injected intramuscularly. There was significant retention and local diffusion of the immune globulin at the injection site and significant radiotracer could still be detected at the site 24 h later. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：289 / 292
页数：4
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