Genetic and biochemical studies of phosphatase activity of PhoR

被引：48
作者：
Carmany, DO [1 ]
Hollingsworth, K [1 ]
McCleary, WR [1 ]
机构：
[1] Brigham Young Univ, Microbiol & Mol Biol Dept, Provo, UT 84602 USA
来源：
JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 03期
关键词：
D O I：
10.1128/JB.185.3.1112-1115.2003
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In Escherichia coli, PhoR is the histidine kinase of the phosphate regulon. It has been postulated that PhoR may function as a phospho-PhoB phosphatase. Experiments with four precise phoR deletion mutants supported this hypothesis and suggested that this activity resides within the histidine phosphorylation domain. This biochemical activity was confirmed by using a separately expressed histidine phosphorylation domain.
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页码：1112 / 1115
页数：4
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