Palladium-catalyzed Heck and Suzuki coupling in glycerol

被引：82
|
作者：
Wolfson, A. [1 ]
Dlugy, C. [1 ]
机构：
[1] Sami Shamoon Coll Engn, Dept Chem Engn, Green Proc Ctr, IL-84100 Beer Sheva, Israel
来源：
CHEMICAL PAPERS | 2007年 / 61卷 / 03期
关键词：
Pd cross coupling; Heck reaction; Suzuki reaction; green solvent; liquid-liquid extraction;
D O I：
10.2478/s11696-007-0026-3
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Heck coupling of halobenzenes with various alkenes and the Suzuki cross coupling of halobenzenes with phenylboronic acid were successfully performed in glycerol as the reaction solvent using homogeneous and heterogeneous palladium catalysts. Glycerol is a renewable and recyclable green solvent that is able to dissolve organic substrates, inorganic bases, and palladium complexes, and that allows easy isolation of the reaction product by simple extraction with glycerol-immiscible solvents such as diethyl ether, hexane, and dichloromethane.
引用
收藏
页码：228 / 232
页数：5
相关论文
共 50 条
  • [1] Palladium-catalyzed heck and suzuki coupling in glycerol
    A. Wolfson
    C. Dlugy
    Chemical Papers, 2007, 61 : 228 - 232
  • [2] Ligand effects in palladium-catalyzed Suzuki and Heck coupling reactions
    Hanhan, M. Emre
    APPLIED ORGANOMETALLIC CHEMISTRY, 2008, 22 (05) : 270 - 275
  • [3] Enantioselective Palladium-Catalyzed Cascade Narasaka-Heck Cyclization/Suzuki Coupling Reaction
    Ye, Wenshao
    Cao, Kangning
    Ye, Zihao
    Qi, Shutao
    Yang, Junfeng
    Zhang, Junliang
    ACS CATALYSIS, 2025, 15 (03): : 2516 - 2521
  • [4] Enantioselective Dicarbofunctionalization of Unactivated Alkenes by Palladium-Catalyzed Tandem Heck/Suzuki Coupling Reaction
    Zhang, Zhan-Ming
    Xu, Bing
    Wu, Lizuo
    Wu, Yuanqi
    Qian, Yanyan
    Zhou, Lujia
    Liu, Yu
    Zhang, Junliang
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (41) : 14653 - 14659
  • [5] Computational Studies of Versatile Heterogeneous Palladium-Catalyzed Suzuki, Heck, and Sonogashira Coupling Reactions
    Veerakumar, Pitchaimani
    Thanasekaran, Pounraj
    Lu, Kuang-Lieh
    Lin, King-Chuen
    Rajagopal, Seenivasan
    ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2017, 5 (10): : 8475 - 8490
  • [6] Palladium-Catalyzed Reductive Heck Coupling of Alkenes
    Oxtoby, Lucas J.
    Gurak, John A., Jr.
    Wisniewski, Steven R.
    Eastgate, Martin D.
    Engle, Keary M.
    TRENDS IN CHEMISTRY, 2019, 1 (06): : 572 - 587
  • [7] BIFURANS VIA PALLADIUM-CATALYZED SUZUKI COUPLING
    Zhang, Jun
    Ye, Peijun
    He, Lu
    Yuan, Ting
    Liu, Qiancai
    HETEROCYCLES, 2015, 91 (11) : 2190 - 2196
  • [8] Synthesis of Dihydropyrrole Derivatives by a Palladium-Catalyzed Heck and Suzuki Cross-Coupling Cascade Reaction
    Peng, Jinsong
    Zhao, Yan
    Zhou, Jingjie
    Ding, Yuehang
    Chen, Chunxia
    SYNTHESIS-STUTTGART, 2014, 46 (15): : 2051 - 2056
  • [9] HECK VERSUS SUZUKI PALLADIUM-CATALYZED CROSS-COUPLING OF A VINYLBORONATE ESTER WITH ARYL HALIDES
    HUNT, AR
    STEWART, SK
    WHITING, A
    TETRAHEDRON LETTERS, 1993, 34 (22) : 3599 - 3602
  • [10] Enantioselective Synthesis of Isoindolinone by Sequential Palladium-Catalyzed Aza-Heck/Suzuki Coupling Reaction
    Wang, Lei
    Zhang, Wenyu
    Wu, Shuaijie
    Wu, Qing
    Han, Ying
    Yan, Chao-Guo
    Zhang, Guodong
    ORGANIC LETTERS, 2024, 27 (01) : 235 - 240
12345