Chronic Hepatitis C Virus Infection in Children

被引:36
作者
Mohan, Neelam [2 ]
Gonzalez-Peralta, Regino P. [3 ]
Fujisawa, Tomoo [4 ]
Chang, Wei-Hwei [5 ]
Heller, Solange [6 ]
Jara, Paloma [7 ]
Kelly, Deirdre [8 ,9 ]
Mieli-Vergani, Giorgina [10 ]
Shah, Uzma [11 ]
Murray, Karen F. [1 ]
机构
[1] Seattle Childrens, Hepatobiliary Program, Seattle, WA 98105 USA
[2] Sir Ganga Ram Hosp, Ctr Child Hlth, Dept Pediat, New Delhi, India
[3] Univ Florida, Coll Med, Div Pediat Gastroenterol Hepatol & Nutr, Gainesville, FL USA
[4] Yokohama E Hosp, Childrens Ctr Hlth & Dev, Yokohama, Kanagawa, Japan
[5] Natl Taiwan Univ Hosp, Dept Pediat, Taipei 10016, Taiwan
[6] Hosp Infantil Mexico Dr Federico Gomez, Dept Gastroenterol & Nutr, Mexico City, DF, Mexico
[7] Pediat Univ Hosp La Paz, Madrid, Spain
[8] Birmingham Childrens Hosp NHS Trust, Liver Unit, Birmingham, W Midlands, England
[9] Univ Birmingham, Birmingham, W Midlands, England
[10] Kings Coll Hosp London, Paediat Liver Ctr, London, England
[11] Dubai Ctr, Harvard Med Sch, Dubai, U Arab Emirates
关键词
chronic hepatitis C; hepatitis; hepatitis C virus; pediatrics; viral infection; ALPHA-2B PLUS RIBAVIRIN; QUALITY-OF-LIFE; SUSTAINED VIROLOGICAL RESPONSE; T-CELL RESPONSES; VERTICAL TRANSMISSION; HEPATOCELLULAR-CARCINOMA; PEGINTERFERON ALPHA-2A; INTERFERON-ALPHA; COMBINATION THERAPY; INITIAL TREATMENT;
D O I
10.1097/MPG.0b013e3181c61995
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The importance of hepatitis C viral infection in the health care of children has grown in recent decades. More is now known about the epidemiology of this infection in children and the progression of disease in the pediatric age group, and the treatment options arc increasing. In this review, we update readers on the state of our understanding of hepatitis C infection in children, provide the current recommendations for monitoring and treatment, an discuss emerging therapies.
引用
收藏
页码:123 / 131
页数:9
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